Gene Ontology (GO)-based weighting
To upload your own network, choose "Upload..." in the advanced options. Your network
must be for one of the GeneMANIA supported organisms and must use one of the supported
Gene IDs, including Entrez, Ensembl, UniProt/SwissProt, RefSeq,
or gene symbols.
File format: tab delimited text (this is a "Save As" option in Excel). The file should
contain either two or three columns and each line corresponds to one interaction.
Self-interactions are ignored.
Format of two column file:
Gene ID <tab> Gene ID
Format of three column file:
Gene ID <tab> Gene ID <tab> Score
Scores: A score is a positive number that corresponds to a measure of confidence or
strength in the interaction: A higher score means more confidence or strength. A
two-column file—a protein-protein interaction network, for example—is equivalent to a
three-column file with the score set to 1.0 for each line.
We recommend only including
interactions above a threshold to reduce the size of the network, especially for correlation
based scores. The help section describes how we assigned
interaction scores for the GeneMANIA network.
15 October 2013 20:00:00
8 December 2013 10:26:06