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Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number. Wang et al. (2006). Cancer Res.
Source: Pearson correlation with 231,830 interactions from GEO
Tags:
Multiclass cancer diagnosis using tumor gene expression signatures. Ramaswamy et al. (2001). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 226,615 interactions from supplementary material
Tags:
Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia. Radtke et al. (2009). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 377,767 interactions from GEO
Tags:
Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis. Gobble et al. (2011). Cancer Res.
Source: Pearson correlation with 449,507 interactions from GEO
Tags:
Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia. Kang et al. (2010). Blood.
Source: Pearson correlation with 549,783 interactions from GEO
Tags:
A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. Hummel et al. (2006). N Engl J Med.
Source: Pearson correlation with 466,765 interactions from GEO
Tags:
Gene signatures of progression and metastasis in renal cell cancer. Jones et al. (2005). Clin Cancer Res.
Source: Pearson correlation with 365,428 interactions from GEO
Tags:
Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Bild et al. (2006). Nature.
Note: One of 3 datasets produced from this publication.
Source: Pearson correlation with 254,105 interactions from GEO
Tags:
Regional variation in gene expression in the healthy colon is dysregulated in ulcerative colitis. Noble et al. (2008). Gut.
Source: Pearson correlation with 603,016 interactions from GEO
The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle. Wu et al. (2007). Endocrine.
Source: Pearson correlation with 223,988 interactions from GEO
Tags:
Gene expression analysis of soft tissue sarcomas: characterization and reclassification of malignant fibrous histiocytoma. Nakayama et al. (2007). Mod Pathol.
Source: Pearson correlation with 361,398 interactions from GEO
Tags:
Tumor cell gene expression changes following short-term in vivo exposure to single agent chemotherapeutics are related to survival in multiple myeloma. Burington et al. (2008). Clin Cancer Res.
Source: Pearson correlation with 266,464 interactions from GEO
Tags:
Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells. Burczynski et al. (2006). J Mol Diagn.
Source: Pearson correlation with 419,356 interactions from GEO
Transcriptome signature of resistance exercise adaptations: mixed muscle and fiber type specific profiles in young and old adults. Raue et al. (2012). J Appl Physiol.
Source: Pearson correlation with 483,849 interactions from GEO
Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage. Rieger et al. (2004). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 220,846 interactions from GEO
Tags:
Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment. Arijs et al. (2009). PLoS One.
Source: Pearson correlation with 570,210 interactions from GEO
Tags:
Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers. Peng et al. (2009). BMC Genomics.
Source: Pearson correlation with 349,954 interactions from GEO
Tags:
Gene expression changes in the course of normal brain aging are sexually dimorphic. Berchtold et al. (2008). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 507,933 interactions from GEO
Tags:
Gene expression profiling and response signatures associated with differential responses to infliximab treatment in ulcerative colitis. Toedter et al. (2011). Am J Gastroenterol.
Source: Pearson correlation with 572,082 interactions from GEO
Tags:
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Perou et al. (1999). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 50,804 interactions from supplementary material
Tags:
Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays. Johnson et al. (2003). Science.
Source: Pearson correlation with 426,934 interactions from GEO
Tags:
A comprehensive transcript index of the human genome generated using microarrays and computational approaches. Schadt et al. (2004). Genome Biol.
Note: Predicted transcript array
Source: Pearson correlation with 60,454 interactions from GEO
Source: Direct interaction with 171 interactions from iRefIndex
Source: Direct interaction with 345 interactions from BioGRID
A human functional protein interaction network and its application to cancer data analysis. Wu et al. (2010). Genome Biol.
Source: 78,448 interactions from supplementary material
Tags:
Source: Direct interaction with 24,924 interactions from Pathway Commons
Source: Direct interaction with 937 interactions from Pathway Commons
Source: Direct interaction with 10,118 interactions from Pathway Commons
Source: Direct interaction with 598 interactions from Pathway Commons
Source: Direct interaction with 685 interactions from Pathway Commons
Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. Behzadnia et al. (2007). EMBO J.
Source: Direct interaction with 101 interactions from iRefIndex
Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. Kneissl et al. (2003). J Mol Biol.
Source: Direct interaction with 83 interactions from iRefIndex
Tags:
Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions. McFarland et al. (2008). Mol Cell Proteomics.
Source: Direct interaction with 152 interactions from iRefIndex
Tags:
Systematic analysis of human protein complexes identifies chromosome segregation proteins. Hutchins et al. (2010). Science.
Source: Direct interaction with 141 interactions from iRefIndex
Tags:
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Jeronimo et al. (2007). Mol Cell.
Source: Direct interaction with 660 interactions from iRefIndex
Tags:
Self-assembling protein microarrays. Ramachandran et al. (2004). Science.
Source: Direct interaction with 119 interactions from iRefIndex
A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein. Goudreault et al. (2009). Mol Cell Proteomics.
Source: Direct interaction with 242 interactions from iRefIndex
Tags:
A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. Sato et al. (2004). Mol Cell.
Source: Direct interaction with 235 interactions from iRefIndex
Tags:
Large-scale structural analysis of the classical human protein tyrosine phosphatome. Barr et al. (2009). Cell.
Source: Direct interaction with 177 interactions from iRefIndex
Source: Direct interaction with 385 interactions from iRefIndex
A quantitative protein interaction network for the ErbB receptors using protein microarrays. Jones et al. (2006). Nature.
Source: Direct interaction with 139 interactions from iRefIndex
Tags:
Defining the human deubiquitinating enzyme interaction landscape. Sowa et al. (2009). Cell.
Note: One of 2 datasets produced from this publication.
Source: Direct interaction with 1,511 interactions from BioGRID
Source: Direct interaction with 41,955 interactions from iRefIndex
Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2. Cannavo et al. (2007). J Biol Chem.
Source: Direct interaction with 109 interactions from iRefIndex
Tags:
Source: Direct interaction with 28,821 interactions from BioGRID
Source: Direct interaction with 12,700 interactions from iRefIndex
Source: Direct interaction with 5,310 interactions from iRefIndex
Source: Direct interaction with 637 interactions from iRefIndex
Source: Direct interaction with 21,448 interactions from iRefIndex
RNA and RNA binding proteins participate in early stages of cell spreading through spreading initiation centers. de Hoog et al. (2004). Cell.
Source: Direct interaction with 220 interactions from iRefIndex
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. Svendsen et al. (2009). Cell.
Source: Direct interaction with 233 interactions from iRefIndex
Tags:
Source: Direct interaction with 13,341 interactions from iRefIndex
An integrated workflow for charting the human interaction proteome: insights into the PP2A system. Glatter et al. (2009). Mol Syst Biol.
Source: Direct interaction with 307 interactions from iRefIndex
Tags:
High-throughput mapping of a dynamic signaling network in mammalian cells. Barrios-Rodiles et al. (2005). Science.
Source: Direct interaction with 547 interactions from iRefIndex
Tags:
Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi. Chen et al. (2009). Proc Natl Acad Sci U S A.
Note: I2D predictions of protein protein interactions using Chen-Pawson-2009 Mus musculus data
Source: Direct interaction with 30 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 567 interactions from I2D
BioGRID: a general repository for interaction datasets. Stark et al. (2006). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using BioGRID Saccharomyces cerevisiae data
Source: Direct interaction with 13,434 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 1,196 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 15 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 3,001 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 16,074 interactions from I2D
A gene-coexpression network for global discovery of conserved genetic modules. Stuart et al. (2003). Science.
Source: 24,952 interactions from supplementary material
Tags:
High-quality binary protein interaction map of the yeast interactome network. Yu et al. (2008). Science.
Note: I2D predictions of protein protein interactions using Yu Gold Standard Saccharomyces cerevisiae data
Source: Direct interaction with 386 interactions from I2D
Tags:
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Rattus norvegicus data
Source: Direct interaction with 1,054 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Mus musculus data
Source: Direct interaction with 977 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Rattus norvegicus data
Source: Direct interaction with 574 interactions from I2D
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Mus musculus data
Source: Direct interaction with 3,422 interactions from I2D
BioGRID: a general repository for interaction datasets. Stark et al. (2006). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using BioGRID Mus musculus data
Source: Direct interaction with 288 interactions from I2D
Ontological visualization of protein-protein interactions. Drabkin et al. (2005). BMC Bioinformatics.
Note: I2D predictions of protein protein interactions using MGI Mus musculus data
Source: Direct interaction with 724 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 103 interactions from I2D
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Drosophila melanogaster data
Source: Direct interaction with 3,920 interactions from I2D
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Rattus norvegicus data
Source: Direct interaction with 556 interactions from I2D
Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Tewari et al. (2004). Mol Cell.
Note: I2D predictions of protein protein interactions usingTewari-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 18 interactions from I2D
Tags:
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Saccharomyces cerevisiae data
Source: Direct interaction with 1,543 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Caenorhabditis elegans data
Source: Direct interaction with 1,166 interactions from I2D
InnateDB: facilitating systems-level analyses of the mammalian innate immune response. Lynn et al. (2008). Mol Syst Biol.
Note: I2D predictions of protein protein interactions using INNATEDB Mus musculus data
Source: Direct interaction with 1,455 interactions from I2D
Tags:
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Caenorhabditis elegans data
Source: Direct interaction with 911 interactions from I2D
An in vivo map of the yeast protein interactome. Tarassov et al. (2008). Science.
Note: I2D predictions of protein protein interactions using Tarassov-Michnick-2008 Saccharomyces cerevisiae data
Source: Direct interaction with 441 interactions from I2D
Tags:
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Krogan et al. (2006). Nature.
Note: I2D predictions of protein protein interactions using Krogan-Greenblatt-2006 Saccharomyces cerevisiae data
Source: Direct interaction with 1,794 interactions from I2D
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Mus musculus data
Source: Direct interaction with 1,198 interactions from I2D
Source: Pearson correlation with 530,357 interactions from Pfam
Source: Pearson correlation with 488,822 interactions from InterPro
cone-rod homeobox [Source:HGNC Symbol;Acc:2383]
Functions:
Synonyms: ENSG00000105392; ENSP00000221996; ENSP00000440389; ENSP00000445565; ENSP00000450582; ENSP00000450840; 1406; CRX; NP_000545; NM_000554; CORD2; LCA7; CRX_HUMAN; O43186;
More at Entrez
neural retina leucine zipper [Source:HGNC Symbol;Acc:8002]
Functions:
Synonyms: ENSG00000129535; ENSP00000380191; ENSP00000380193; ENSP00000380197; ENSP00000452966; ENSP00000454062; ENSP00000454180; 4901; NRL; NP_006168; NM_006177; D14S46E; NRL-MAF; RP27; NRL_HUMAN; P54845;
More at Entrez
chromosome 2 open reading frame 65 [Source:HGNC Symbol;Acc:25183]
Functions:
Synonyms: ENSG00000159374; ENSP00000290536; ENSP00000351213; ENSP00000386793; ENSP00000406107; ENSP00000408713; ENSP00000414882; ENSP00000445662; 130951; C2orf65; NP_620159; NM_138804; D6Mm5e; CB065_HUMAN; Q8TC57;
More at Entrez
retina and anterior neural fold homeobox 2 [Source:HGNC Symbol;Acc:18286]
Functions:
Synonyms: ENSG00000173976; ENSP00000378538; ENSP00000450456; ENSP00000450687; 84839; RAX2; NP_116142; NM_032753; ARMD6; CORD11; MGC15631; QRX; RAXL1; Q96IS3; RAX2_HUMAN;
More at Entrez
importin 13 [Source:HGNC Symbol;Acc:16853]
Functions:
Synonyms: ENSG00000117408; ENSP00000361414; ENSP00000361418; 9670; IPO13; NP_055467; XP_003403768; NM_014652; XM_003403720; IMP13; KAP13; KIAA0724; RANBP13; IPO13_HUMAN; O94829;
More at Entrez
phosducin [Source:HGNC Symbol;Acc:8759]
Functions:
Synonyms: ENSG00000116703; ENSP00000342033; ENSP00000375855; ENSP00000411564; ENSP00000422775; 5132; PDC; NP_002588; NP_072098; NM_002597; NM_022576; NM_022577; MEKA; PHD; PhLOP; P20941; PHOS_HUMAN;
More at Entrez
Sp4 transcription factor [Source:HGNC Symbol;Acc:11209]
Functions:
Synonyms: ENSG00000105866; ENSP00000222584; ENSP00000390817; ENSP00000393623; ENSP00000402421; 6671; SP4; NP_003103; NM_003112; HF1B; MGC130008; MGC130009; SPR-1; Q02446; SP4_HUMAN;
More at Entrez
crystallin, beta B1 [Source:HGNC Symbol;Acc:2397]
Functions:
Synonyms: ENSG00000100122; ENSP00000215939; 1414; CRYBB1; NP_001878; NM_001887; CATCN3; CRBB1_HUMAN; P53674;
More at Entrez
guanylate cyclase activator 1A (retina) [Source:HGNC Symbol;Acc:4678]
Functions:
Synonyms: ENSG00000048545; ENSP00000053469; ENSP00000362049; ENSP00000362056; ENSP00000377784; ENSP00000388438; ENSP00000437476; 2978; GUCA1A; NP_000400; NM_000409; C6orf131; CORD14; dJ139D8.6; GCAP1; GUCA; GUCA1; GUC1A_HUMAN; P43080;
More at Entrez
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 [Source:HGNC Symbol;Acc:4393]
Functions:
Synonyms: ENSG00000114349; ENSP00000232461; ENSP00000387555; ENSP00000403537; 2779; GNAT1; NP_000163; NP_653082; NM_000172; NM_144499; CSNBAD3; GBT1; GNATR; GNAT1_HUMAN; P11488;
More at Entrez
retinol dehydrogenase 5 (11-cis/9-cis) [Source:HGNC Symbol;Acc:9940]
Functions:
Synonyms: ENSG00000135437; ENSP00000257895; ENSP00000447128; ENSP00000447513; ENSP00000448014; ENSP00000449927; 5959; RDH5; NP_001186700; NP_002896; NM_001199771; NM_002905; HSD17B9; RDH1; SDR9C5; Q92781; RDH1_HUMAN;
More at Entrez
PDZK1 interacting protein 1 [Source:HGNC Symbol;Acc:16887]
Functions:
Synonyms: ENSG00000162366; ENSP00000294338; ENSP00000360952; 10158; PDZK1IP1; NP_005755; NM_005764; DD96; MAP17; RP1-18D14.5; SPAP; PDZ1I_HUMAN; Q13113;
More at Entrez
neuro-oncological ventral antigen 2 [Source:HGNC Symbol;Acc:7887]
Functions:
Synonyms: ENSG00000104967; ENSP00000263257; 4858; NOVA2; NP_002507; NM_002516; ANOVA; NOVA3; NOVA2_HUMAN; Q9UNW9;
More at Entrez
zinc finger RNA binding protein 2 [Source:HGNC Symbol;Acc:29189]
Functions:
Synonyms: ENSG00000105278; ENSP00000262961; ENSP00000388567; ENSP00000388974; 23217; ZFR2; NP_001139112; NP_055989; NM_001145640; NM_015174; NR_027149; KIAA1086; Q9UPR6; ZFR2_HUMAN;
More at Entrez
retinal outer segment membrane protein 1 [Source:HGNC Symbol;Acc:10254]
Functions:
Synonyms: ENSG00000149489; ENSP00000278833; ENSP00000432151; ENSP00000432983; ENSP00000433566; 6094; ROM1; NP_000318; NM_000327; ROM; ROSP1; TSPAN23; Q03395; ROM1_HUMAN;
More at Entrez
S-antigen; retina and pineal gland (arrestin) [Source:HGNC Symbol;Acc:10521]
Functions:
Synonyms: ENSG00000130561; ENSP00000252857; ENSP00000386444; ENSP00000392889; ENSP00000404733; ENSP00000408937; ENSP00000409475; ENSP00000439496; 6295; SAG; NP_000532; NM_000541; ARRESTIN; RP47; S-AG; ARRS_HUMAN; P10523;
More at Entrez
crystallin, alpha A [Source:HGNC Symbol;Acc:2388]
Functions:
Synonyms: ENSG00000160202; ENSP00000291554; ENSP00000381200; ENSP00000381201; 1409; CRYAA; NP_000385; NM_000394; CRYA1; HSPB4; CRYAA_HUMAN; P02489;
More at Entrez
orthodenticle homeobox 2 [Source:HGNC Symbol;Acc:8522]
Functions:
Synonyms: ENSG00000165588; ENSP00000343819; ENSP00000386185; ENSP00000450468; ENSP00000451272; ENSP00000451357; ENSP00000452336; 5015; OTX2; NP_068374; NP_758840; NM_021728; NM_172337; CPHD6; MCOPS5; OTX2_HUMAN; P32243;
More at Entrez
crystallin, beta B2 [Source:HGNC Symbol;Acc:2398]
Functions:
Synonyms: ENSG00000244752; ENSP00000381273; 1415; CRYBB2; NP_000487; NM_000496; CCA2; CRYB2; CRYB2A; D22S665; CRBB2_HUMAN; P43320;
More at Entrez
coagulation factor II (thrombin) receptor-like 2 [Source:HGNC Symbol;Acc:3539]
Functions:
Synonyms: ENSG00000164220; ENSP00000296641; ENSP00000426703; 2151; F2RL2; NP_004092; NM_004101; O00254; PAR3_HUMAN;
More at Entrez
gamma-aminobutyric acid (GABA) receptor, rho 1 [Source:HGNC Symbol;Acc:4090]
Functions:
Synonyms: ENSG00000146276; ENSP00000358463; ENSP00000394687; ENSP00000400355; ENSP00000410130; ENSP00000412673; 2569; GABRR1; NP_002033; NM_002042; GBRR1_HUMAN; P24046;
More at Entrez
| query genes | n/a | 1 / 1 |
| detection of light stimulus | 1.73E-2 | 3 / 23 |
| visual perception | 1.73E-2 | 4 / 98 |
| sensory perception of light stimulus | 1.73E-2 | 4 / 99 |
| phototransduction | 1.73E-2 | 3 / 19 |
| detection of abiotic stimulus | 2.72E-2 | 3 / 35 |
| detection of external stimulus | 5.21E-2 | 3 / 46 |
| LRR domain binding | 2.03E-1 | 2 / 12 |
| sensory perception | 2.47E-1 | 4 / 232 |
| detection of visible light | 2.51E-1 | 2 / 15 |
| response to light stimulus | 4.48E-1 | 3 / 112 |
3.1.1
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8417ED4DF2F89DD2B138B1D8D97E64D4.genemania