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Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number. Wang et al. (2006). Cancer Res.
Source: Pearson correlation with 231,830 interactions from GEO
Tags:
Multiclass cancer diagnosis using tumor gene expression signatures. Ramaswamy et al. (2001). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 226,615 interactions from supplementary material
Tags:
Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia. Radtke et al. (2009). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 377,767 interactions from GEO
Tags:
Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis. Gobble et al. (2011). Cancer Res.
Source: Pearson correlation with 449,507 interactions from GEO
Tags:
Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia. Kang et al. (2010). Blood.
Source: Pearson correlation with 549,783 interactions from GEO
Tags:
A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. Hummel et al. (2006). N Engl J Med.
Source: Pearson correlation with 466,765 interactions from GEO
Tags:
Gene signatures of progression and metastasis in renal cell cancer. Jones et al. (2005). Clin Cancer Res.
Source: Pearson correlation with 365,428 interactions from GEO
Tags:
Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Bild et al. (2006). Nature.
Note: One of 3 datasets produced from this publication.
Source: Pearson correlation with 254,105 interactions from GEO
Tags:
Regional variation in gene expression in the healthy colon is dysregulated in ulcerative colitis. Noble et al. (2008). Gut.
Source: Pearson correlation with 603,016 interactions from GEO
The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle. Wu et al. (2007). Endocrine.
Source: Pearson correlation with 223,988 interactions from GEO
Tags:
Gene expression analysis of soft tissue sarcomas: characterization and reclassification of malignant fibrous histiocytoma. Nakayama et al. (2007). Mod Pathol.
Source: Pearson correlation with 361,398 interactions from GEO
Tags:
Tumor cell gene expression changes following short-term in vivo exposure to single agent chemotherapeutics are related to survival in multiple myeloma. Burington et al. (2008). Clin Cancer Res.
Source: Pearson correlation with 266,464 interactions from GEO
Tags:
Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells. Burczynski et al. (2006). J Mol Diagn.
Source: Pearson correlation with 419,356 interactions from GEO
Transcriptome signature of resistance exercise adaptations: mixed muscle and fiber type specific profiles in young and old adults. Raue et al. (2012). J Appl Physiol.
Source: Pearson correlation with 483,849 interactions from GEO
Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage. Rieger et al. (2004). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 220,846 interactions from GEO
Tags:
Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment. Arijs et al. (2009). PLoS One.
Source: Pearson correlation with 570,210 interactions from GEO
Tags:
Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers. Peng et al. (2009). BMC Genomics.
Source: Pearson correlation with 349,954 interactions from GEO
Tags:
Gene expression changes in the course of normal brain aging are sexually dimorphic. Berchtold et al. (2008). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 507,933 interactions from GEO
Tags:
Gene expression profiling and response signatures associated with differential responses to infliximab treatment in ulcerative colitis. Toedter et al. (2011). Am J Gastroenterol.
Source: Pearson correlation with 572,082 interactions from GEO
Tags:
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Perou et al. (1999). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 50,804 interactions from supplementary material
Tags:
Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays. Johnson et al. (2003). Science.
Source: Pearson correlation with 426,934 interactions from GEO
Tags:
A comprehensive transcript index of the human genome generated using microarrays and computational approaches. Schadt et al. (2004). Genome Biol.
Note: Predicted transcript array
Source: Pearson correlation with 60,454 interactions from GEO
Source: Direct interaction with 171 interactions from iRefIndex
Source: Direct interaction with 345 interactions from BioGRID
A human functional protein interaction network and its application to cancer data analysis. Wu et al. (2010). Genome Biol.
Source: 78,448 interactions from supplementary material
Tags:
Source: Direct interaction with 24,924 interactions from Pathway Commons
Source: Direct interaction with 937 interactions from Pathway Commons
Source: Direct interaction with 10,118 interactions from Pathway Commons
Source: Direct interaction with 598 interactions from Pathway Commons
Source: Direct interaction with 685 interactions from Pathway Commons
Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. Behzadnia et al. (2007). EMBO J.
Source: Direct interaction with 101 interactions from iRefIndex
Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. Kneissl et al. (2003). J Mol Biol.
Source: Direct interaction with 83 interactions from iRefIndex
Tags:
Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions. McFarland et al. (2008). Mol Cell Proteomics.
Source: Direct interaction with 152 interactions from iRefIndex
Tags:
Systematic analysis of human protein complexes identifies chromosome segregation proteins. Hutchins et al. (2010). Science.
Source: Direct interaction with 141 interactions from iRefIndex
Tags:
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Jeronimo et al. (2007). Mol Cell.
Source: Direct interaction with 660 interactions from iRefIndex
Tags:
Self-assembling protein microarrays. Ramachandran et al. (2004). Science.
Source: Direct interaction with 119 interactions from iRefIndex
A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein. Goudreault et al. (2009). Mol Cell Proteomics.
Source: Direct interaction with 242 interactions from iRefIndex
Tags:
A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. Sato et al. (2004). Mol Cell.
Source: Direct interaction with 235 interactions from iRefIndex
Tags:
Large-scale structural analysis of the classical human protein tyrosine phosphatome. Barr et al. (2009). Cell.
Source: Direct interaction with 177 interactions from iRefIndex
Source: Direct interaction with 385 interactions from iRefIndex
A quantitative protein interaction network for the ErbB receptors using protein microarrays. Jones et al. (2006). Nature.
Source: Direct interaction with 139 interactions from iRefIndex
Tags:
Defining the human deubiquitinating enzyme interaction landscape. Sowa et al. (2009). Cell.
Note: One of 2 datasets produced from this publication.
Source: Direct interaction with 1,511 interactions from BioGRID
Source: Direct interaction with 41,955 interactions from iRefIndex
Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2. Cannavo et al. (2007). J Biol Chem.
Source: Direct interaction with 109 interactions from iRefIndex
Tags:
Source: Direct interaction with 28,821 interactions from BioGRID
Source: Direct interaction with 12,700 interactions from iRefIndex
Source: Direct interaction with 5,310 interactions from iRefIndex
Source: Direct interaction with 637 interactions from iRefIndex
Source: Direct interaction with 21,448 interactions from iRefIndex
RNA and RNA binding proteins participate in early stages of cell spreading through spreading initiation centers. de Hoog et al. (2004). Cell.
Source: Direct interaction with 220 interactions from iRefIndex
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. Svendsen et al. (2009). Cell.
Source: Direct interaction with 233 interactions from iRefIndex
Tags:
Source: Direct interaction with 13,341 interactions from iRefIndex
An integrated workflow for charting the human interaction proteome: insights into the PP2A system. Glatter et al. (2009). Mol Syst Biol.
Source: Direct interaction with 307 interactions from iRefIndex
Tags:
High-throughput mapping of a dynamic signaling network in mammalian cells. Barrios-Rodiles et al. (2005). Science.
Source: Direct interaction with 547 interactions from iRefIndex
Tags:
Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi. Chen et al. (2009). Proc Natl Acad Sci U S A.
Note: I2D predictions of protein protein interactions using Chen-Pawson-2009 Mus musculus data
Source: Direct interaction with 30 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 567 interactions from I2D
BioGRID: a general repository for interaction datasets. Stark et al. (2006). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using BioGRID Saccharomyces cerevisiae data
Source: Direct interaction with 13,434 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 1,196 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 15 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 3,001 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 16,074 interactions from I2D
A gene-coexpression network for global discovery of conserved genetic modules. Stuart et al. (2003). Science.
Source: 24,952 interactions from supplementary material
Tags:
High-quality binary protein interaction map of the yeast interactome network. Yu et al. (2008). Science.
Note: I2D predictions of protein protein interactions using Yu Gold Standard Saccharomyces cerevisiae data
Source: Direct interaction with 386 interactions from I2D
Tags:
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Rattus norvegicus data
Source: Direct interaction with 1,054 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Mus musculus data
Source: Direct interaction with 977 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Rattus norvegicus data
Source: Direct interaction with 574 interactions from I2D
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Mus musculus data
Source: Direct interaction with 3,422 interactions from I2D
BioGRID: a general repository for interaction datasets. Stark et al. (2006). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using BioGRID Mus musculus data
Source: Direct interaction with 288 interactions from I2D
Ontological visualization of protein-protein interactions. Drabkin et al. (2005). BMC Bioinformatics.
Note: I2D predictions of protein protein interactions using MGI Mus musculus data
Source: Direct interaction with 724 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 103 interactions from I2D
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Drosophila melanogaster data
Source: Direct interaction with 3,920 interactions from I2D
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Rattus norvegicus data
Source: Direct interaction with 556 interactions from I2D
Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Tewari et al. (2004). Mol Cell.
Note: I2D predictions of protein protein interactions usingTewari-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 18 interactions from I2D
Tags:
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Saccharomyces cerevisiae data
Source: Direct interaction with 1,543 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Caenorhabditis elegans data
Source: Direct interaction with 1,166 interactions from I2D
InnateDB: facilitating systems-level analyses of the mammalian innate immune response. Lynn et al. (2008). Mol Syst Biol.
Note: I2D predictions of protein protein interactions using INNATEDB Mus musculus data
Source: Direct interaction with 1,455 interactions from I2D
Tags:
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Caenorhabditis elegans data
Source: Direct interaction with 911 interactions from I2D
An in vivo map of the yeast protein interactome. Tarassov et al. (2008). Science.
Note: I2D predictions of protein protein interactions using Tarassov-Michnick-2008 Saccharomyces cerevisiae data
Source: Direct interaction with 441 interactions from I2D
Tags:
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Krogan et al. (2006). Nature.
Note: I2D predictions of protein protein interactions using Krogan-Greenblatt-2006 Saccharomyces cerevisiae data
Source: Direct interaction with 1,794 interactions from I2D
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Mus musculus data
Source: Direct interaction with 1,198 interactions from I2D
Source: Pearson correlation with 530,357 interactions from Pfam
Source: Pearson correlation with 488,822 interactions from InterPro
chromosome 9 open reading frame 72 [Source:HGNC Symbol;Acc:28337]
Functions:
Synonyms: ENSG00000147894; ENSP00000369331; ENSP00000369333; ENSP00000369339; 203228; C9orf72; NP_001242983; NP_060795; NP_659442; NM_001256054; NM_018325; NM_145005; ALSFTD; FTDALS; MGC23980; CI072_HUMAN; Q96LT7;
More at Entrez
GDNF-inducible zinc finger protein 1 [Source:HGNC Symbol;Acc:15808]
Functions:
Synonyms: ENSG00000125812; ENSP00000338290; ENSP00000366250; ENSP00000410009; ENSP00000445118; ENSP00000445458; 64412; GZF1; NP_071927; NM_022482; dJ322G13.2; ZBTB23; ZNF336; GZF1_HUMAN; Q9H116;
More at Entrez
protein phosphatase 1, regulatory subunit 3B [Source:HGNC Symbol;Acc:14942]
Functions:
Synonyms: ENSG00000173281; ENSP00000308318; ENSP00000428642; 79660; PPP1R3B; NP_001188258; NP_078883; NM_001201329; NM_024607; FLJ14005; PPP1R4; PPR3B_HUMAN; Q86XI6;
More at Entrez
GLI pathogenesis-related 2 [Source:HGNC Symbol;Acc:18007]
Functions:
Synonyms: ENSG00000122694; ENSP00000367195; ENSP00000367196; ENSP00000379857; 152007; GLIPR2; NP_071738; NM_022343; C9orf19; GAPR-1; GAPR1_HUMAN; Q9H4G4;
More at Entrez
pleckstrin [Source:HGNC Symbol;Acc:9070]
Functions:
Synonyms: ENSG00000115956; ENSP00000234313; 5341; PLEK; NP_002655; NM_002664; P08567; PLEK_HUMAN;
More at Entrez
p21 protein (Cdc42/Rac)-activated kinase 1 [Source:HGNC Symbol;Acc:8590]
Functions:
Synonyms: ENSG00000149269; ENSP00000278568; ENSP00000348696; ENSP00000431541; ENSP00000431906; ENSP00000432477; ENSP00000433004; ENSP00000433211; ENSP00000433423; ENSP00000433518; ENSP00000433737; ENSP00000435983; ENSP00000437261; 5058; PAK1; NP_001122092; NP_002567; NM_001128620; NM_002576; PAKalpha; PAK1_HUMAN; Q13153;
More at Entrez
cat eye syndrome chromosome region, candidate 1 [Source:HGNC Symbol;Acc:1839]
Functions:
Synonyms: ENSG00000093072; ENSP00000262607; ENSP00000332871; ENSP00000382731; ENSP00000382733; ENSP00000390523; ENSP00000392078; ENSP00000406443; ENSP00000417811; ENSP00000442482; 51816; CECR1; NP_059120; NP_803124; NM_017424; NM_177405; ADGF; IDGFL; CECR1_HUMAN; Q9NZK5;
More at Entrez
chemokine (C-X-C motif) receptor 7 [Source:HGNC Symbol;Acc:23692]
Functions:
Synonyms: ENSG00000144476; ENSP00000272928; ENSP00000405945; 57007; CXCR7; NP_064707; NM_001047841; NM_020311; CMKOR1; GPR159; CXCR7_HUMAN; P25106;
More at Entrez
CKLF-like MARVEL transmembrane domain containing 2 [Source:HGNC Symbol;Acc:19173]
Functions:
Synonyms: ENSG00000140932; ENSP00000268595; ENSP00000368800; 146225; CMTM2; NP_001186246; NP_653274; NM_001199317; NM_144673; CKLFSF2; FLJ25732; MGC39436; CKLF2_HUMAN; Q8TAZ6;
More at Entrez
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) [Source:HGNC Symbol;Acc:5969]
Functions:
Synonyms: ENSG00000168811; ENSP00000303231; ENSP00000419046; ENSP00000420184; 3592; IL12A; NP_000873; NM_000882; IL-12A; NFSK; NKSF1; IL12A_HUMAN; P29459;
More at Entrez
phosphodiesterase 4B, cAMP-specific [Source:HGNC Symbol;Acc:8781]
Functions:
Synonyms: ENSG00000184588; ENSP00000332116; ENSP00000342637; ENSP00000360084; ENSP00000360088; ENSP00000392947; ENSP00000397548; ENSP00000431909; ENSP00000432400; ENSP00000432592; ENSP00000436104; ENSP00000437249; 5142; PDE4B; NP_001032416; NP_001032417; NP_001032418; NP_002591; NM_001037339; NM_001037340; NM_001037341; NM_002600; DPDE4; PDE4B5; PDEIVB; PDE4B_HUMAN; Q07343;
More at Entrez
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Source:HGNC Symbol;Acc:26429]
Functions:
Synonyms: ENSG00000181381; ENSP00000260184; ENSP00000421026; ENSP00000422202; ENSP00000422423; ENSP00000422920; ENSP00000424310; ENSP00000424396; ENSP00000427386; 91351; DDX60L; NP_001012985; NM_001012967; FLJ31033; DDX6L_HUMAN; Q5H9U9;
More at Entrez
interleukin 13 receptor, alpha 1 [Source:HGNC Symbol;Acc:5974]
Functions:
Synonyms: ENSG00000131724; ENSP00000360700; ENSP00000360705; ENSP00000360730; 3597; IL13RA1; NP_001551; NM_001560; CD213A1; IL-13Ra; NR4; I13R1_HUMAN; P78552;
More at Entrez
regulator of G-protein signaling 18 [Source:HGNC Symbol;Acc:14261]
Functions:
Synonyms: ENSG00000150681; ENSP00000356430; 64407; RGS18; NP_570138; NM_130782; Q9NS28; RGS18_HUMAN;
More at Entrez
inositol polyphosphate multikinase [Source:HGNC Symbol;Acc:20739]
Functions:
Synonyms: ENSG00000151151; ENSP00000363046; 253430; IPMK; NP_689416; NM_152230; IPMK_HUMAN; Q8NFU5;
More at Entrez
family with sequence similarity 69, member A [Source:HGNC Symbol;Acc:32213]
Functions:
Synonyms: ENSG00000154511; ENSP00000359333; ENSP00000383809; 388650; FAM69A; NP_001006606; NP_001239198; NP_001239199; NP_001239200; NP_001239202; NM_001006605; NM_001252269; NM_001252270; NM_001252271; NM_001252273; FLJ23493; FA69A_HUMAN; Q5T7M9;
More at Entrez
vesicle transport through interaction with t-SNAREs homolog 1A (yeast) [Source:HGNC Symbol;Acc:17792]
Functions:
Synonyms: ENSG00000151532; ENSP00000376792; ENSP00000395017; 143187; VTI1A; NP_660207; NM_145206; MVti1; Vti1-rp2; VTI1RP2; Q96AJ9; VTI1A_HUMAN;
More at Entrez
branched chain amino-acid transaminase 1, cytosolic [Source:HGNC Symbol;Acc:976]
Functions:
Synonyms: ENSG00000060982; ENSP00000261192; ENSP00000339805; ENSP00000438593; ENSP00000440817; ENSP00000440827; ENSP00000443459; 586; BCAT1; NP_001171562; NP_001171563; NP_001171564; NP_001171565; NP_005495; NM_001178091; NM_001178092; NM_001178093; NM_001178094; NM_005504; BCATC; BCT1; ECA39; MECA39; PNAS121; BCAT1_HUMAN; P54687;
More at Entrez
spermatogenesis associated, serine-rich 2-like [Source:HGNC Symbol;Acc:24574]
Functions:
Synonyms: ENSG00000196141; ENSP00000351503; ENSP00000353989; ENSP00000386310; ENSP00000386336; ENSP00000386391; ENSP00000386600; ENSP00000386730; ENSP00000386931; ENSP00000387333; ENSP00000389908; ENSP00000390506; ENSP00000391467; ENSP00000396109; ENSP00000398198; ENSP00000402559; ENSP00000405506; ENSP00000405751; ENSP00000406728; ENSP00000411294; ENSP00000413142; ENSP00000413648; 26010; SPATS2L; NP_001093892; NP_001093893; NP_001093894; NP_056350; NM_001100422; NM_001100423; NM_001100424; NM_015535; DNAPTP6; SGNP; Q9NUQ6; SPS2L_HUMAN;
More at Entrez
toll-like receptor 2 [Source:HGNC Symbol;Acc:11848]
Functions:
Synonyms: ENSG00000137462; ENSP00000260010; 7097; TLR2; NP_003255; NM_003264; CD282; TIL4; O60603; TLR2_HUMAN;
More at Entrez
telomeric repeat binding factor 2 [Source:HGNC Symbol;Acc:11729]
Functions:
Synonyms: ENSG00000132604; ENSP00000254942; 7014; TERF2; NP_005643; NM_005652; TRBF2; Q15554; TERF2_HUMAN;
More at Entrez
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D463F1DF0376765756294AA09F7A69A8.genemania