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Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number. Wang et al. (2006). Cancer Res.
Source: Pearson correlation with 231,830 interactions from GEO
Tags:
Multiclass cancer diagnosis using tumor gene expression signatures. Ramaswamy et al. (2001). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 226,615 interactions from supplementary material
Tags:
Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia. Radtke et al. (2009). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 377,767 interactions from GEO
Tags:
Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis. Gobble et al. (2011). Cancer Res.
Source: Pearson correlation with 449,507 interactions from GEO
Tags:
Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia. Kang et al. (2010). Blood.
Source: Pearson correlation with 549,783 interactions from GEO
Tags:
A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. Hummel et al. (2006). N Engl J Med.
Source: Pearson correlation with 466,765 interactions from GEO
Tags:
Gene signatures of progression and metastasis in renal cell cancer. Jones et al. (2005). Clin Cancer Res.
Source: Pearson correlation with 365,428 interactions from GEO
Tags:
Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Bild et al. (2006). Nature.
Note: One of 3 datasets produced from this publication.
Source: Pearson correlation with 254,105 interactions from GEO
Tags:
Regional variation in gene expression in the healthy colon is dysregulated in ulcerative colitis. Noble et al. (2008). Gut.
Source: Pearson correlation with 603,016 interactions from GEO
The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle. Wu et al. (2007). Endocrine.
Source: Pearson correlation with 223,988 interactions from GEO
Tags:
Gene expression analysis of soft tissue sarcomas: characterization and reclassification of malignant fibrous histiocytoma. Nakayama et al. (2007). Mod Pathol.
Source: Pearson correlation with 361,398 interactions from GEO
Tags:
Tumor cell gene expression changes following short-term in vivo exposure to single agent chemotherapeutics are related to survival in multiple myeloma. Burington et al. (2008). Clin Cancer Res.
Source: Pearson correlation with 266,464 interactions from GEO
Tags:
Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells. Burczynski et al. (2006). J Mol Diagn.
Source: Pearson correlation with 419,356 interactions from GEO
Transcriptome signature of resistance exercise adaptations: mixed muscle and fiber type specific profiles in young and old adults. Raue et al. (2012). J Appl Physiol.
Source: Pearson correlation with 483,849 interactions from GEO
Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage. Rieger et al. (2004). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 220,846 interactions from GEO
Tags:
Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment. Arijs et al. (2009). PLoS One.
Source: Pearson correlation with 570,210 interactions from GEO
Tags:
Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers. Peng et al. (2009). BMC Genomics.
Source: Pearson correlation with 349,954 interactions from GEO
Tags:
Gene expression changes in the course of normal brain aging are sexually dimorphic. Berchtold et al. (2008). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 507,933 interactions from GEO
Tags:
Gene expression profiling and response signatures associated with differential responses to infliximab treatment in ulcerative colitis. Toedter et al. (2011). Am J Gastroenterol.
Source: Pearson correlation with 572,082 interactions from GEO
Tags:
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Perou et al. (1999). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 50,804 interactions from supplementary material
Tags:
Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays. Johnson et al. (2003). Science.
Source: Pearson correlation with 426,934 interactions from GEO
Tags:
A comprehensive transcript index of the human genome generated using microarrays and computational approaches. Schadt et al. (2004). Genome Biol.
Note: Predicted transcript array
Source: Pearson correlation with 60,454 interactions from GEO
Source: Direct interaction with 171 interactions from iRefIndex
Source: Direct interaction with 345 interactions from BioGRID
A human functional protein interaction network and its application to cancer data analysis. Wu et al. (2010). Genome Biol.
Source: 78,448 interactions from supplementary material
Tags:
Source: Direct interaction with 24,924 interactions from Pathway Commons
Source: Direct interaction with 937 interactions from Pathway Commons
Source: Direct interaction with 10,118 interactions from Pathway Commons
Source: Direct interaction with 598 interactions from Pathway Commons
Source: Direct interaction with 685 interactions from Pathway Commons
Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. Behzadnia et al. (2007). EMBO J.
Source: Direct interaction with 101 interactions from iRefIndex
Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. Kneissl et al. (2003). J Mol Biol.
Source: Direct interaction with 83 interactions from iRefIndex
Tags:
Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions. McFarland et al. (2008). Mol Cell Proteomics.
Source: Direct interaction with 152 interactions from iRefIndex
Tags:
Systematic analysis of human protein complexes identifies chromosome segregation proteins. Hutchins et al. (2010). Science.
Source: Direct interaction with 141 interactions from iRefIndex
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Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Jeronimo et al. (2007). Mol Cell.
Source: Direct interaction with 660 interactions from iRefIndex
Tags:
Self-assembling protein microarrays. Ramachandran et al. (2004). Science.
Source: Direct interaction with 119 interactions from iRefIndex
A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein. Goudreault et al. (2009). Mol Cell Proteomics.
Source: Direct interaction with 242 interactions from iRefIndex
Tags:
A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. Sato et al. (2004). Mol Cell.
Source: Direct interaction with 235 interactions from iRefIndex
Tags:
Large-scale structural analysis of the classical human protein tyrosine phosphatome. Barr et al. (2009). Cell.
Source: Direct interaction with 177 interactions from iRefIndex
Source: Direct interaction with 385 interactions from iRefIndex
A quantitative protein interaction network for the ErbB receptors using protein microarrays. Jones et al. (2006). Nature.
Source: Direct interaction with 139 interactions from iRefIndex
Tags:
Defining the human deubiquitinating enzyme interaction landscape. Sowa et al. (2009). Cell.
Note: One of 2 datasets produced from this publication.
Source: Direct interaction with 1,511 interactions from BioGRID
Source: Direct interaction with 41,955 interactions from iRefIndex
Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2. Cannavo et al. (2007). J Biol Chem.
Source: Direct interaction with 109 interactions from iRefIndex
Tags:
Source: Direct interaction with 28,821 interactions from BioGRID
Source: Direct interaction with 12,700 interactions from iRefIndex
Source: Direct interaction with 5,310 interactions from iRefIndex
Source: Direct interaction with 637 interactions from iRefIndex
Source: Direct interaction with 21,448 interactions from iRefIndex
RNA and RNA binding proteins participate in early stages of cell spreading through spreading initiation centers. de Hoog et al. (2004). Cell.
Source: Direct interaction with 220 interactions from iRefIndex
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. Svendsen et al. (2009). Cell.
Source: Direct interaction with 233 interactions from iRefIndex
Tags:
Source: Direct interaction with 13,341 interactions from iRefIndex
An integrated workflow for charting the human interaction proteome: insights into the PP2A system. Glatter et al. (2009). Mol Syst Biol.
Source: Direct interaction with 307 interactions from iRefIndex
Tags:
High-throughput mapping of a dynamic signaling network in mammalian cells. Barrios-Rodiles et al. (2005). Science.
Source: Direct interaction with 547 interactions from iRefIndex
Tags:
Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi. Chen et al. (2009). Proc Natl Acad Sci U S A.
Note: I2D predictions of protein protein interactions using Chen-Pawson-2009 Mus musculus data
Source: Direct interaction with 30 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 567 interactions from I2D
BioGRID: a general repository for interaction datasets. Stark et al. (2006). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using BioGRID Saccharomyces cerevisiae data
Source: Direct interaction with 13,434 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 1,196 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 15 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 3,001 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 16,074 interactions from I2D
A gene-coexpression network for global discovery of conserved genetic modules. Stuart et al. (2003). Science.
Source: 24,952 interactions from supplementary material
Tags:
High-quality binary protein interaction map of the yeast interactome network. Yu et al. (2008). Science.
Note: I2D predictions of protein protein interactions using Yu Gold Standard Saccharomyces cerevisiae data
Source: Direct interaction with 386 interactions from I2D
Tags:
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Rattus norvegicus data
Source: Direct interaction with 1,054 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Mus musculus data
Source: Direct interaction with 977 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Rattus norvegicus data
Source: Direct interaction with 574 interactions from I2D
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Mus musculus data
Source: Direct interaction with 3,422 interactions from I2D
BioGRID: a general repository for interaction datasets. Stark et al. (2006). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using BioGRID Mus musculus data
Source: Direct interaction with 288 interactions from I2D
Ontological visualization of protein-protein interactions. Drabkin et al. (2005). BMC Bioinformatics.
Note: I2D predictions of protein protein interactions using MGI Mus musculus data
Source: Direct interaction with 724 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 103 interactions from I2D
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Drosophila melanogaster data
Source: Direct interaction with 3,920 interactions from I2D
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Rattus norvegicus data
Source: Direct interaction with 556 interactions from I2D
Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Tewari et al. (2004). Mol Cell.
Note: I2D predictions of protein protein interactions usingTewari-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 18 interactions from I2D
Tags:
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Saccharomyces cerevisiae data
Source: Direct interaction with 1,543 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Caenorhabditis elegans data
Source: Direct interaction with 1,166 interactions from I2D
InnateDB: facilitating systems-level analyses of the mammalian innate immune response. Lynn et al. (2008). Mol Syst Biol.
Note: I2D predictions of protein protein interactions using INNATEDB Mus musculus data
Source: Direct interaction with 1,455 interactions from I2D
Tags:
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Caenorhabditis elegans data
Source: Direct interaction with 911 interactions from I2D
An in vivo map of the yeast protein interactome. Tarassov et al. (2008). Science.
Note: I2D predictions of protein protein interactions using Tarassov-Michnick-2008 Saccharomyces cerevisiae data
Source: Direct interaction with 441 interactions from I2D
Tags:
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Krogan et al. (2006). Nature.
Note: I2D predictions of protein protein interactions using Krogan-Greenblatt-2006 Saccharomyces cerevisiae data
Source: Direct interaction with 1,794 interactions from I2D
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Mus musculus data
Source: Direct interaction with 1,198 interactions from I2D
Source: Pearson correlation with 530,357 interactions from Pfam
Source: Pearson correlation with 488,822 interactions from InterPro
F-box and WD repeat domain containing 11 [Source:HGNC Symbol;Acc:13607]
Functions:
Synonyms: ENSG00000072803; ENSP00000265094; ENSP00000296933; ENSP00000377391; ENSP00000427777; ENSP00000428753; ENSP00000429818; ENSP00000430104; ENSP00000431100; ENSP00000444929; 23291; FBXW11; NP_036432; NP_387448; NP_387449; NM_012300; NM_033644; NM_033645; BTRC2; BTRCP2; Fbw11; FBW1B; FBXW1B; KIAA0696; FBW1B_HUMAN; Q9UKB1;
More at Entrez
KH domain containing, RNA binding, signal transduction associated 2 [Source:HGNC Symbol;Acc:18114]
Functions:
Synonyms: ENSG00000112232; ENSP00000281156; ENSP00000443437; 202559; KHDRBS2; NP_689901; NM_152688; bA535F17.1; MGC26664; SLM-1; SLM1; KHDR2_HUMAN; Q5VWX1;
More at Entrez
S-phase kinase-associated protein 1 [Source:HGNC Symbol;Acc:10899]
Functions:
Synonyms: ENSG00000113558; ENSP00000231487; ENSP00000331708; ENSP00000428962; ENSP00000429415; ENSP00000429472; ENSP00000429686; ENSP00000429961; ENSP00000429995; ENSP00000429996; ENSP00000430774; ENSP00000430885; ENSP00000431067; 6500; SKP1; NP_008861; NP_733779; NM_006930; NM_170679; EMC19; MGC34403; OCP-II; OCP2; p19A; SKP1A; TCEB1L; P63208; SKP1_HUMAN;
More at Entrez
casein kinase 1, alpha 1 [Source:HGNC Symbol;Acc:2451]
Functions:
Synonyms: ENSG00000113712; ENSP00000261798; ENSP00000367074; ENSP00000385776; ENSP00000421268; ENSP00000421689; ENSP00000425366; ENSP00000426747; ENSP00000427031; ENSP00000430252; 1452; CSNK1A1; NP_001020276; NP_001883; NM_001025105; NM_001892; CK1a; CK1alpha; CKIa; CKIalpha; HLCDGP1; PRO2975; KC1A_HUMAN; P48729;
More at Entrez
family with sequence similarity 123B [Source:HGNC Symbol;Acc:26837]
Functions:
Synonyms: ENSG00000184675; ENSP00000329117; ENSP00000364003; ENSP00000384722; 139285; FAM123B; NP_689637; NM_152424; AMER1; FLJ39827; OSCS; RP11-403E24.2; WTX; F123B_HUMAN; Q5JTC6;
More at Entrez
beta-transducin repeat containing [Source:HGNC Symbol;Acc:1144]
Functions:
Synonyms: ENSG00000166167; ENSP00000359202; ENSP00000359206; ENSP00000377088; ENSP00000385339; ENSP00000437608; 8945; BTRC; NP_003930; NP_378663; NM_003939; NM_033637; BETA-TRCP; beta-TrCP1; betaTrCP; bTrCP; bTrCP1; FBW1A; FBXW1; FBXW1A; FWD1; FBW1A_HUMAN; Q9Y297;
More at Entrez
anterior pharynx defective 1 homolog A (C. elegans) [Source:HGNC Symbol;Acc:29509]
Functions:
Synonyms: ENSG00000117362; ENSP00000236017; ENSP00000353380; ENSP00000358105; ENSP00000397473; 51107; APH1A; NP_001071096; NP_001230700; NP_001230701; NP_057106; NM_001077628; NM_001243771; NM_001243772; NM_016022; NR_045033; NR_045034; NR_045035; 6530402N02Rik; APH-1; APH-1A; CGI-78; APH1A_HUMAN; Q96BI3;
More at Entrez
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) [Source:HGNC Symbol;Acc:689]
Functions:
Synonyms: ENSG00000166233; ENSP00000299305; ENSP00000369217; 25820; ARIH1; NP_005735; NM_005744; ARI; HARI; HHARI; UBCH7BP; ARI1_HUMAN; Q9Y4X5;
More at Entrez
presenilin enhancer 2 homolog (C. elegans) [Source:HGNC Symbol;Acc:30100]
Functions:
Synonyms: ENSG00000205155; ENSP00000222266; 55851; PSENEN; NP_758844; NM_172341; MSTP064; PEN-2; PEN2; PEN2_HUMAN; Q9NZ42;
More at Entrez
cullin 1 [Source:HGNC Symbol;Acc:2551]
Functions:
Synonyms: ENSG00000055130; ENSP00000326804; ENSP00000387160; ENSP00000396011; ENSP00000441340; 8454; CUL1; NP_003583; NM_003592; CUL1_HUMAN; Q13616;
More at Entrez
anterior pharynx defective 1 homolog B (C. elegans) [Source:HGNC Symbol;Acc:24080]
Functions:
Synonyms: ENSG00000138613; ENSP00000261879; ENSP00000369697; ENSP00000369700; ENSP00000453002; ENSP00000453327; ENSP00000453516; 83464; APH1B; NP_001139118; NP_112591; NM_001145646; NM_031301; APH-1B; DKFZp564D0372; PRO1328; PSFL; TAAV688; APH1B_HUMAN; Q8WW43;
More at Entrez
human immunodeficiency virus type I enhancer binding protein 2 [Source:HGNC Symbol;Acc:4921]
Functions:
Synonyms: ENSG00000010818; ENSP00000012134; ENSP00000356575; ENSP00000356576; 3097; HIVEP2; NP_006725; NM_006734; HIV-EP2; MBP-2; MIBP1; Schnurri-2; SHN2; ZAS2; ZNF40B; P31629; ZEP2_HUMAN;
More at Entrez
A kinase (PRKA) anchor protein 11 [Source:HGNC Symbol;Acc:369]
Functions:
Synonyms: ENSG00000023516; ENSP00000025301; 11215; AKAP11; NP_057332; NM_016248; NM_144490; AKAP-11; AKAP220; DKFZp781I12161; FLJ11304; KIAA0629; PPP1R44; PRKA11; AKA11_HUMAN; Q9UKA4;
More at Entrez
GLI family zinc finger 2 [Source:HGNC Symbol;Acc:4318]
Functions:
Synonyms: ENSG00000074047; ENSP00000312694; ENSP00000344473; ENSP00000354586; ENSP00000390436; ENSP00000395688; ENSP00000397488; ENSP00000398992; ENSP00000400593; ENSP00000402383; ENSP00000403715; ENSP00000415773; ENSP00000441454; 2736; GLI2; NP_005261; NM_005270; NM_030379; NM_030380; NM_030381; HPE9; THP1; THP2; GLI2_HUMAN; P10070;
More at Entrez
reprimo, TP53 dependent G2 arrest mediator candidate [Source:HGNC Symbol;Acc:24201]
Functions:
Synonyms: ENSG00000177519; ENSP00000314946; 56475; RPRM; NP_062819; NM_019845; FLJ90327; REPRIMO; Q9NS64; RPRM_HUMAN;
More at Entrez
1-acylglycerol-3-phosphate O-acyltransferase 3 [Source:HGNC Symbol;Acc:326]
Functions:
Synonyms: ENSG00000160216; ENSP00000291572; ENSP00000332989; ENSP00000381135; ENSP00000381138; ENSP00000381140; ENSP00000389318; ENSP00000394102; ENSP00000394881; ENSP00000412079; ENSP00000413906; ENSP00000414440; ENSP00000443510; 56894; AGPAT3; NP_001032642; NP_064517; NM_001037553; NM_020132; LPAAT-gamma; LPAAT-GAMMA1; PLCC_HUMAN; Q9NRZ7;
More at Entrez
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha [Source:HGNC Symbol;Acc:7797]
Functions:
Synonyms: ENSG00000100906; ENSP00000216797; ENSP00000450514; ENSP00000450537; ENSP00000451257; ENSP00000451281; 4792; NFKBIA; NP_065390; NM_020529; IkappaBalpha; IKBA; MAD-3; NFKBI; IKBA_HUMAN; P25963;
More at Entrez
presenilin 1 [Source:HGNC Symbol;Acc:9508]
Functions:
Synonyms: ENSG00000080815; ENSP00000261970; ENSP00000326366; ENSP00000339523; ENSP00000350342; ENSP00000377712; ENSP00000377719; ENSP00000385948; ENSP00000450551; ENSP00000450652; ENSP00000450845; ENSP00000451347; ENSP00000451429; ENSP00000451498; ENSP00000451588; ENSP00000451662; ENSP00000451674; ENSP00000451880; ENSP00000451915; ENSP00000452128; ENSP00000452242; ENSP00000452267; ENSP00000452477; ENSP00000453466; ENSP00000454156; 5663; PSEN1; NP_000012; NP_015557; NM_000021; NM_007318; NM_007319; PS-1; PS1; S182; P49768; PSN1_HUMAN;
More at Entrez
CCR4-NOT transcription complex, subunit 8 [Source:HGNC Symbol;Acc:9207]
Functions:
Synonyms: ENSG00000155508; ENSP00000285896; ENSP00000384747; ENSP00000428090; ENSP00000428305; ENSP00000428359; ENSP00000428550; ENSP00000428565; ENSP00000428576; ENSP00000428600; ENSP00000428842; ENSP00000429108; ENSP00000429310; ENSP00000429394; ENSP00000429576; ENSP00000429810; ENSP00000429882; ENSP00000430215; ENSP00000430493; ENSP00000430833; ENSP00000431034; ENSP00000442762; 9337; CNOT8; NP_004770; NM_004779; CALIF; hCAF1; CNOT8_HUMAN; Q9UFF9;
More at Entrez
protein phosphatase 2, catalytic subunit, alpha isozyme [Source:HGNC Symbol;Acc:9299]
Functions:
Synonyms: ENSG00000113575; ENSP00000418447; ENSP00000428816; ENSP00000430869; 5515; PPP2CA; NP_002706; NM_002715; PP2Ac; RP-C; P67775; PP2AA_HUMAN;
More at Entrez
nicastrin [Source:HGNC Symbol;Acc:17091]
Functions:
Synonyms: ENSG00000162736; ENSP00000294785; ENSP00000357042; ENSP00000357044; ENSP00000357046; ENSP00000376047; ENSP00000388118; ENSP00000389370; ENSP00000390409; ENSP00000407849; ENSP00000410124; ENSP00000415442; ENSP00000442605; 23385; NCSTN; NP_056146; NM_015331; KIAA0253; NICA_HUMAN; Q92542;
More at Entrez
| query genes | n/a | 1 / 1 |
| aspartic-type endopeptidase activity | 4.54E-9 | 5 / 12 |
| aspartic-type peptidase activity | 4.54E-9 | 5 / 12 |
| membrane protein intracellular domain proteolysis | 4.54E-9 | 5 / 11 |
| Notch receptor processing | 1.29E-8 | 5 / 15 |
| amyloid precursor protein catabolic process | 8.24E-7 | 4 / 10 |
| membrane protein proteolysis | 1.41E-6 | 5 / 38 |
| glycoprotein catabolic process | 3.81E-6 | 4 / 15 |
| Notch signaling pathway | 3.95E-6 | 5 / 49 |
| amyloid precursor protein metabolic process | 3.95E-6 | 4 / 16 |
| protein processing | 1.07E-5 | 5 / 62 |
| SCF ubiquitin ligase complex | 1.29E-5 | 4 / 22 |
| protein maturation | 1.92E-5 | 5 / 72 |
| membrane protein ectodomain proteolysis | 3.54E-5 | 4 / 29 |
| nerve growth factor receptor signaling pathway | 1.16E-4 | 6 / 216 |
| induction of apoptosis by extracellular signals | 1.37E-4 | 5 / 111 |
| ubiquitin ligase complex | 1.9E-4 | 5 / 120 |
| endopeptidase activity | 3.59E-4 | 5 / 138 |
| SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 4.26E-4 | 3 / 14 |
| cullin-RING ubiquitin ligase complex | 9.61E-4 | 4 / 71 |
| ubiquitin-dependent protein catabolic process | 7.56E-3 | 5 / 265 |
| modification-dependent protein catabolic process | 7.61E-3 | 5 / 268 |
| modification-dependent macromolecule catabolic process | 7.67E-3 | 5 / 271 |
| peptidase activity, acting on L-amino acid peptides | 7.74E-3 | 5 / 274 |
| proteolysis involved in cellular protein catabolic process | 8.47E-3 | 5 / 283 |
| peptidase activity | 8.47E-3 | 5 / 284 |
| cellular protein catabolic process | 9.31E-3 | 5 / 292 |
| proteasomal ubiquitin-dependent protein catabolic process | 3.37E-2 | 4 / 190 |
| ubiquitin-protein ligase activity | 3.52E-2 | 4 / 194 |
| proteasomal protein catabolic process | 3.61E-2 | 4 / 197 |
| positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 3.94E-2 | 3 / 72 |
| small conjugating protein ligase activity | 3.94E-2 | 4 / 205 |
| acid-amino acid ligase activity | 4.59E-2 | 4 / 215 |
| regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 4.64E-2 | 3 / 78 |
| positive regulation of ubiquitin-protein ligase activity | 4.68E-2 | 3 / 79 |
| positive regulation of ligase activity | 5.08E-2 | 3 / 82 |
| anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 5.12E-2 | 3 / 83 |
| protein destabilization | 5.28E-2 | 2 / 14 |
| ligase activity, forming carbon-nitrogen bonds | 5.55E-2 | 4 / 236 |
| glycoprotein metabolic process | 6.15E-2 | 4 / 244 |
| regulation of ubiquitin-protein ligase activity | 6.26E-2 | 3 / 92 |
| regulation of ligase activity | 6.72E-2 | 3 / 95 |
| ligase activity | 9.88E-2 | 4 / 283 |
| positive regulation of protein ubiquitination | 9.88E-2 | 3 / 110 |
3.1.1
19 July 2012 20:00:00
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