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Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number. Wang et al. (2006). Cancer Res.
Source: Pearson correlation with 231,830 interactions from GEO
Tags:
Multiclass cancer diagnosis using tumor gene expression signatures. Ramaswamy et al. (2001). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 226,615 interactions from supplementary material
Tags:
Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia. Radtke et al. (2009). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 377,767 interactions from GEO
Tags:
Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis. Gobble et al. (2011). Cancer Res.
Source: Pearson correlation with 449,507 interactions from GEO
Tags:
Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia. Kang et al. (2010). Blood.
Source: Pearson correlation with 549,783 interactions from GEO
Tags:
A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. Hummel et al. (2006). N Engl J Med.
Source: Pearson correlation with 466,765 interactions from GEO
Tags:
Gene signatures of progression and metastasis in renal cell cancer. Jones et al. (2005). Clin Cancer Res.
Source: Pearson correlation with 365,428 interactions from GEO
Tags:
Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Bild et al. (2006). Nature.
Note: One of 3 datasets produced from this publication.
Source: Pearson correlation with 254,105 interactions from GEO
Tags:
Regional variation in gene expression in the healthy colon is dysregulated in ulcerative colitis. Noble et al. (2008). Gut.
Source: Pearson correlation with 603,016 interactions from GEO
The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle. Wu et al. (2007). Endocrine.
Source: Pearson correlation with 223,988 interactions from GEO
Tags:
Gene expression analysis of soft tissue sarcomas: characterization and reclassification of malignant fibrous histiocytoma. Nakayama et al. (2007). Mod Pathol.
Source: Pearson correlation with 361,398 interactions from GEO
Tags:
Tumor cell gene expression changes following short-term in vivo exposure to single agent chemotherapeutics are related to survival in multiple myeloma. Burington et al. (2008). Clin Cancer Res.
Source: Pearson correlation with 266,464 interactions from GEO
Tags:
Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells. Burczynski et al. (2006). J Mol Diagn.
Source: Pearson correlation with 419,356 interactions from GEO
Transcriptome signature of resistance exercise adaptations: mixed muscle and fiber type specific profiles in young and old adults. Raue et al. (2012). J Appl Physiol.
Source: Pearson correlation with 483,849 interactions from GEO
Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage. Rieger et al. (2004). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 220,846 interactions from GEO
Tags:
Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment. Arijs et al. (2009). PLoS One.
Source: Pearson correlation with 570,210 interactions from GEO
Tags:
Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers. Peng et al. (2009). BMC Genomics.
Source: Pearson correlation with 349,954 interactions from GEO
Tags:
Gene expression changes in the course of normal brain aging are sexually dimorphic. Berchtold et al. (2008). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 507,933 interactions from GEO
Tags:
Gene expression profiling and response signatures associated with differential responses to infliximab treatment in ulcerative colitis. Toedter et al. (2011). Am J Gastroenterol.
Source: Pearson correlation with 572,082 interactions from GEO
Tags:
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Perou et al. (1999). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 50,804 interactions from supplementary material
Tags:
Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays. Johnson et al. (2003). Science.
Source: Pearson correlation with 426,934 interactions from GEO
Tags:
A comprehensive transcript index of the human genome generated using microarrays and computational approaches. Schadt et al. (2004). Genome Biol.
Note: Predicted transcript array
Source: Pearson correlation with 60,454 interactions from GEO
Source: Direct interaction with 171 interactions from iRefIndex
Source: Direct interaction with 345 interactions from BioGRID
A human functional protein interaction network and its application to cancer data analysis. Wu et al. (2010). Genome Biol.
Source: 78,448 interactions from supplementary material
Tags:
Source: Direct interaction with 24,924 interactions from Pathway Commons
Source: Direct interaction with 937 interactions from Pathway Commons
Source: Direct interaction with 10,118 interactions from Pathway Commons
Source: Direct interaction with 598 interactions from Pathway Commons
Source: Direct interaction with 685 interactions from Pathway Commons
Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. Behzadnia et al. (2007). EMBO J.
Source: Direct interaction with 101 interactions from iRefIndex
Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. Kneissl et al. (2003). J Mol Biol.
Source: Direct interaction with 83 interactions from iRefIndex
Tags:
Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions. McFarland et al. (2008). Mol Cell Proteomics.
Source: Direct interaction with 152 interactions from iRefIndex
Tags:
Systematic analysis of human protein complexes identifies chromosome segregation proteins. Hutchins et al. (2010). Science.
Source: Direct interaction with 141 interactions from iRefIndex
Tags:
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Jeronimo et al. (2007). Mol Cell.
Source: Direct interaction with 660 interactions from iRefIndex
Tags:
Self-assembling protein microarrays. Ramachandran et al. (2004). Science.
Source: Direct interaction with 119 interactions from iRefIndex
A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein. Goudreault et al. (2009). Mol Cell Proteomics.
Source: Direct interaction with 242 interactions from iRefIndex
Tags:
A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. Sato et al. (2004). Mol Cell.
Source: Direct interaction with 235 interactions from iRefIndex
Tags:
Large-scale structural analysis of the classical human protein tyrosine phosphatome. Barr et al. (2009). Cell.
Source: Direct interaction with 177 interactions from iRefIndex
Source: Direct interaction with 385 interactions from iRefIndex
A quantitative protein interaction network for the ErbB receptors using protein microarrays. Jones et al. (2006). Nature.
Source: Direct interaction with 139 interactions from iRefIndex
Tags:
Defining the human deubiquitinating enzyme interaction landscape. Sowa et al. (2009). Cell.
Note: One of 2 datasets produced from this publication.
Source: Direct interaction with 1,511 interactions from BioGRID
Source: Direct interaction with 41,955 interactions from iRefIndex
Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2. Cannavo et al. (2007). J Biol Chem.
Source: Direct interaction with 109 interactions from iRefIndex
Tags:
Source: Direct interaction with 28,821 interactions from BioGRID
Source: Direct interaction with 12,700 interactions from iRefIndex
Source: Direct interaction with 5,310 interactions from iRefIndex
Source: Direct interaction with 637 interactions from iRefIndex
Source: Direct interaction with 21,448 interactions from iRefIndex
RNA and RNA binding proteins participate in early stages of cell spreading through spreading initiation centers. de Hoog et al. (2004). Cell.
Source: Direct interaction with 220 interactions from iRefIndex
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. Svendsen et al. (2009). Cell.
Source: Direct interaction with 233 interactions from iRefIndex
Tags:
Source: Direct interaction with 13,341 interactions from iRefIndex
An integrated workflow for charting the human interaction proteome: insights into the PP2A system. Glatter et al. (2009). Mol Syst Biol.
Source: Direct interaction with 307 interactions from iRefIndex
Tags:
High-throughput mapping of a dynamic signaling network in mammalian cells. Barrios-Rodiles et al. (2005). Science.
Source: Direct interaction with 547 interactions from iRefIndex
Tags:
Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi. Chen et al. (2009). Proc Natl Acad Sci U S A.
Note: I2D predictions of protein protein interactions using Chen-Pawson-2009 Mus musculus data
Source: Direct interaction with 30 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 567 interactions from I2D
BioGRID: a general repository for interaction datasets. Stark et al. (2006). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using BioGRID Saccharomyces cerevisiae data
Source: Direct interaction with 13,434 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 1,196 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 15 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 3,001 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 16,074 interactions from I2D
A gene-coexpression network for global discovery of conserved genetic modules. Stuart et al. (2003). Science.
Source: 24,952 interactions from supplementary material
Tags:
High-quality binary protein interaction map of the yeast interactome network. Yu et al. (2008). Science.
Note: I2D predictions of protein protein interactions using Yu Gold Standard Saccharomyces cerevisiae data
Source: Direct interaction with 386 interactions from I2D
Tags:
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Rattus norvegicus data
Source: Direct interaction with 1,054 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Mus musculus data
Source: Direct interaction with 977 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Rattus norvegicus data
Source: Direct interaction with 574 interactions from I2D
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Mus musculus data
Source: Direct interaction with 3,422 interactions from I2D
BioGRID: a general repository for interaction datasets. Stark et al. (2006). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using BioGRID Mus musculus data
Source: Direct interaction with 288 interactions from I2D
Ontological visualization of protein-protein interactions. Drabkin et al. (2005). BMC Bioinformatics.
Note: I2D predictions of protein protein interactions using MGI Mus musculus data
Source: Direct interaction with 724 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 103 interactions from I2D
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Drosophila melanogaster data
Source: Direct interaction with 3,920 interactions from I2D
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Rattus norvegicus data
Source: Direct interaction with 556 interactions from I2D
Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Tewari et al. (2004). Mol Cell.
Note: I2D predictions of protein protein interactions usingTewari-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 18 interactions from I2D
Tags:
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Saccharomyces cerevisiae data
Source: Direct interaction with 1,543 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Caenorhabditis elegans data
Source: Direct interaction with 1,166 interactions from I2D
InnateDB: facilitating systems-level analyses of the mammalian innate immune response. Lynn et al. (2008). Mol Syst Biol.
Note: I2D predictions of protein protein interactions using INNATEDB Mus musculus data
Source: Direct interaction with 1,455 interactions from I2D
Tags:
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Caenorhabditis elegans data
Source: Direct interaction with 911 interactions from I2D
An in vivo map of the yeast protein interactome. Tarassov et al. (2008). Science.
Note: I2D predictions of protein protein interactions using Tarassov-Michnick-2008 Saccharomyces cerevisiae data
Source: Direct interaction with 441 interactions from I2D
Tags:
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Krogan et al. (2006). Nature.
Note: I2D predictions of protein protein interactions using Krogan-Greenblatt-2006 Saccharomyces cerevisiae data
Source: Direct interaction with 1,794 interactions from I2D
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Mus musculus data
Source: Direct interaction with 1,198 interactions from I2D
Source: Pearson correlation with 530,357 interactions from Pfam
Source: Pearson correlation with 488,822 interactions from InterPro
phospholipase A2, group IIE [Source:HGNC Symbol;Acc:13414]
Functions:
Synonyms: ENSG00000188784; ENSP00000364257; 30814; PLA2G2E; NP_055404; NM_014589; PA2GE_HUMAN; Q9NZK7;
More at Entrez
guanine nucleotide binding protein (G protein) alpha 12 [Source:HGNC Symbol;Acc:4380]
Functions:
Synonyms: ENSG00000146535; ENSP00000275364; ENSP00000380160; ENSP00000385935; ENSP00000386054; ENSP00000391462; ENSP00000437469; 2768; GNA12; NP_031379; NM_007353; GNA12_HUMAN; Q03113;
More at Entrez
phospholipase A2, group IIF [Source:HGNC Symbol;Acc:30040]
Functions:
Synonyms: ENSG00000158786; ENSP00000364243; 64600; PLA2G2F; NP_073730; NM_022819; PA2GF_HUMAN; Q9BZM2;
More at Entrez
guanine nucleotide binding protein (G protein), alpha 13 [Source:HGNC Symbol;Acc:4381]
Functions:
Synonyms: ENSG00000120063; ENSP00000239138; ENSP00000400717; ENSP00000439647; 10672; GNA13; NP_006563; NM_006572; MGC46138; GNA13_HUMAN; Q14344;
More at Entrez
peptide YY [Source:HGNC Symbol;Acc:9748]
Functions:
Synonyms: ENSG00000131096; ENSP00000353198; 5697; PYY; NP_004151; NM_004160; PYY1; P10082; PYY_HUMAN;
More at Entrez
protein kinase C, delta [Source:HGNC Symbol;Acc:9399]
Functions:
Synonyms: ENSG00000163932; ENSP00000331602; ENSP00000378217; ENSP00000418106; ENSP00000419629; ENSP00000419726; 5580; PRKCD; NP_006245; NP_997704; NM_006254; NM_212539; MAY1; nPKC-delta; PKCD; KPCD_HUMAN; Q05655;
More at Entrez
protein interacting with cyclin A1 [Source:HGNC Symbol;Acc:28600]
Functions:
Synonyms: ENSG00000167525; ENSP00000301039; ENSP00000390058; ENSP00000406218; ENSP00000411400; 147011; PROCA1; NP_689678; NM_152465; MGC39650; PRCA1_HUMAN; Q8NCQ7;
More at Entrez
phospholipase A2, group IIC [Source:HGNC Symbol;Acc:9032]
Functions:
Synonyms: ENSG00000187980; ENSP00000247992; ENSP00000389335; 391013; PLA2G2C; NP_001099042; NM_001105572; PA2GC_HUMAN; Q5R387;
More at Entrez
Otoconin-90 [Source:UniProtKB/Swiss-Prot;Acc:Q02509]
Functions:
Synonyms: ENSG00000258417; ENSP00000262283; RP11-240B13.2;
More at Ensembl
otoconin 90 [Source:HGNC Symbol;Acc:8100]
Functions:
Synonyms: ENSG00000253117; ENSP00000254627; ENSP00000390050; 729330; OC90; NP_001073868; NM_001080399;
More at Entrez
chromosome 14 open reading frame 182 [Source:HGNC Symbol;Acc:27503]
Functions:
Synonyms: ENSG00000214900; ENSP00000382157; 283551; C14orf182; NP_001012724; NM_001012706;
More at Entrez
protein kinase C, gamma [Source:HGNC Symbol;Acc:9402]
Functions:
Synonyms: ENSG00000126583; ENSP00000263431; ENSP00000387919; ENSP00000438090; ENSP00000440541; ENSP00000443493; 5582; PRKCG; NP_002730; NM_002739; MGC57564; PKC-gamma; PKCC; PKCG; SCA14; KPCG_HUMAN; P05129;
More at Entrez
BUD13 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:28199]
Functions:
Synonyms: ENSG00000137656; ENSP00000260210; ENSP00000364594; ENSP00000415748; 84811; BUD13; NP_001153208; NP_116114; NM_001159736; NM_032725; fSAP71; MGC13125; BUD13_HUMAN; Q9BRD0;
More at Entrez
G protein-coupled receptor 97 [Source:HGNC Symbol;Acc:13728]
Functions:
Synonyms: ENSG00000182885; ENSP00000331199; ENSP00000332900; ENSP00000404803; 222487; GPR97; NP_740746; NM_170776; PB99; PGR26; GPR97_HUMAN; Q86Y34;
More at Entrez
neuroglobin [Source:HGNC Symbol;Acc:14077]
Functions:
Synonyms: ENSG00000165553; ENSP00000298352; 58157; NGB; NP_067080; NM_021257; NGB_HUMAN; Q9NPG2;
More at Entrez
PR domain containing 11 [Source:HGNC Symbol;Acc:13996]
Functions:
Synonyms: ENSG00000019485; ENSP00000263765; ENSP00000394314; ENSP00000431898; ENSP00000435976; 56981; PRDM11; NP_064614; NM_020229; PFM8; PRD11_HUMAN; Q9NQV5;
More at Entrez
regulator of G-protein signaling 22 [Source:HGNC Symbol;Acc:24499]
Functions:
Synonyms: ENSG00000132554; ENSP00000354109; ENSP00000389751; ENSP00000427754; ENSP00000427798; ENSP00000427930; ENSP00000428212; ENSP00000429198; ENSP00000429382; ENSP00000430378; ENSP00000430903; 26166; RGS22; NP_056483; NM_015668; DKFZP434I092; PRTD-NY2; Q8NE09; RGS22_HUMAN;
More at Entrez
phospholipase A2, group V [Source:HGNC Symbol;Acc:9038]
Functions:
Synonyms: ENSG00000127472; ENSP00000364249; 5322; PLA2G5; NP_000920; NM_000929; GV-PLA2; hVPLA(2); PLA2-10; P39877; PA2G5_HUMAN;
More at Entrez
delta-like 2 homolog (Drosophila) [Source:HGNC Symbol;Acc:21113]
Functions:
Synonyms: ENSG00000171462; ENSP00000349893; ENSP00000361563; ENSP00000361566; ENSP00000361574; ENSP00000398906; ENSP00000399829; 65989; DLK2; NP_076421; NP_996262; NM_023932; NM_206539; EGFL9; MGC2487; DLK2_HUMAN; Q6UY11;
More at Entrez
phospholipase A2, group IID [Source:HGNC Symbol;Acc:9033]
Functions:
Synonyms: ENSG00000117215; ENSP00000364246; 26279; PLA2G2D; NP_036532; NM_012400; sPLA2S; SPLASH; PA2GD_HUMAN; Q9UNK4;
More at Entrez
GNAS complex locus [Source:HGNC Symbol;Acc:4392]
Functions:
Synonyms: ENSG00000087460; ENSP00000265620; ENSP00000265621; ENSP00000302237; ENSP00000304472; ENSP00000323571; ENSP00000345971; ENSP00000346328; ENSP00000360115; ENSP00000360122; ENSP00000360123; ENSP00000360126; ENSP00000360136; ENSP00000360139; ENSP00000360140; ENSP00000360141; ENSP00000360143; ENSP00000392000; ENSP00000412356; ENSP00000412424; ENSP00000416234; 2778; GNAS; NP_000507; NP_001070956; NP_001070957; NP_001070958; NP_057676; NP_536350; NP_536351; NM_000516; NM_001077488; NM_001077489; NM_001077490; NM_016592; NM_080425; NM_080426; NR_003259; AHO; GNAS1; GNASXL; GPSA; GSA; GSP; NESP; NESP55; PHP1A; PHP1B; PHP1C; POH; SCG6; ALEX_HUMAN; GNAS1_HUMAN; GNAS2_HUMAN; GNAS3_HUMAN; O95467; P63092; P84996; Q5JWF2;
More at Entrez
| query genes | n/a | 1 / 1 |
| G-protein beta/gamma-subunit complex binding | 1.18E-2 | 3 / 16 |
| heterotrimeric G-protein complex | 1.61E-2 | 3 / 22 |
| extrinsic to internal side of plasma membrane | 4.14E-2 | 3 / 34 |
| extrinsic to plasma membrane | 1.2E-1 | 3 / 53 |
| G-protein signaling, coupled to cAMP nucleotide second messenger | 1.87E-1 | 3 / 70 |
| platelet activation | 1.87E-1 | 4 / 207 |
| extrinsic to membrane | 1.87E-1 | 3 / 74 |
| internal side of plasma membrane | 1.92E-1 | 3 / 78 |
| cAMP-mediated signaling | 2.12E-1 | 3 / 84 |
| brush border membrane | 2.25E-1 | 2 / 15 |
3.1.1
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88B387D8D2FB0F4B12EAC29930719100.genemania