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Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number. Wang et al. (2006). Cancer Res.
Source: Pearson correlation with 231,830 interactions from GEO
Tags:
Multiclass cancer diagnosis using tumor gene expression signatures. Ramaswamy et al. (2001). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 226,615 interactions from supplementary material
Tags:
Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia. Radtke et al. (2009). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 377,767 interactions from GEO
Tags:
Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis. Gobble et al. (2011). Cancer Res.
Source: Pearson correlation with 449,507 interactions from GEO
Tags:
Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia. Kang et al. (2010). Blood.
Source: Pearson correlation with 549,783 interactions from GEO
Tags:
A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. Hummel et al. (2006). N Engl J Med.
Source: Pearson correlation with 466,765 interactions from GEO
Tags:
Gene signatures of progression and metastasis in renal cell cancer. Jones et al. (2005). Clin Cancer Res.
Source: Pearson correlation with 365,428 interactions from GEO
Tags:
Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Bild et al. (2006). Nature.
Note: One of 3 datasets produced from this publication.
Source: Pearson correlation with 254,105 interactions from GEO
Tags:
Regional variation in gene expression in the healthy colon is dysregulated in ulcerative colitis. Noble et al. (2008). Gut.
Source: Pearson correlation with 603,016 interactions from GEO
The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle. Wu et al. (2007). Endocrine.
Source: Pearson correlation with 223,988 interactions from GEO
Tags:
Gene expression analysis of soft tissue sarcomas: characterization and reclassification of malignant fibrous histiocytoma. Nakayama et al. (2007). Mod Pathol.
Source: Pearson correlation with 361,398 interactions from GEO
Tags:
Tumor cell gene expression changes following short-term in vivo exposure to single agent chemotherapeutics are related to survival in multiple myeloma. Burington et al. (2008). Clin Cancer Res.
Source: Pearson correlation with 266,464 interactions from GEO
Tags:
Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells. Burczynski et al. (2006). J Mol Diagn.
Source: Pearson correlation with 419,356 interactions from GEO
Transcriptome signature of resistance exercise adaptations: mixed muscle and fiber type specific profiles in young and old adults. Raue et al. (2012). J Appl Physiol.
Source: Pearson correlation with 483,849 interactions from GEO
Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage. Rieger et al. (2004). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 220,846 interactions from GEO
Tags:
Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment. Arijs et al. (2009). PLoS One.
Source: Pearson correlation with 570,210 interactions from GEO
Tags:
Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers. Peng et al. (2009). BMC Genomics.
Source: Pearson correlation with 349,954 interactions from GEO
Tags:
Gene expression changes in the course of normal brain aging are sexually dimorphic. Berchtold et al. (2008). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 507,933 interactions from GEO
Tags:
Gene expression profiling and response signatures associated with differential responses to infliximab treatment in ulcerative colitis. Toedter et al. (2011). Am J Gastroenterol.
Source: Pearson correlation with 572,082 interactions from GEO
Tags:
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Perou et al. (1999). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 50,804 interactions from supplementary material
Tags:
Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays. Johnson et al. (2003). Science.
Source: Pearson correlation with 426,934 interactions from GEO
Tags:
A comprehensive transcript index of the human genome generated using microarrays and computational approaches. Schadt et al. (2004). Genome Biol.
Note: Predicted transcript array
Source: Pearson correlation with 60,454 interactions from GEO
Source: Direct interaction with 171 interactions from iRefIndex
Source: Direct interaction with 345 interactions from BioGRID
A human functional protein interaction network and its application to cancer data analysis. Wu et al. (2010). Genome Biol.
Source: 78,448 interactions from supplementary material
Tags:
Source: Direct interaction with 24,924 interactions from Pathway Commons
Source: Direct interaction with 937 interactions from Pathway Commons
Source: Direct interaction with 10,118 interactions from Pathway Commons
Source: Direct interaction with 598 interactions from Pathway Commons
Source: Direct interaction with 685 interactions from Pathway Commons
Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. Behzadnia et al. (2007). EMBO J.
Source: Direct interaction with 101 interactions from iRefIndex
Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. Kneissl et al. (2003). J Mol Biol.
Source: Direct interaction with 83 interactions from iRefIndex
Tags:
Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions. McFarland et al. (2008). Mol Cell Proteomics.
Source: Direct interaction with 152 interactions from iRefIndex
Tags:
Systematic analysis of human protein complexes identifies chromosome segregation proteins. Hutchins et al. (2010). Science.
Source: Direct interaction with 141 interactions from iRefIndex
Tags:
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Jeronimo et al. (2007). Mol Cell.
Source: Direct interaction with 660 interactions from iRefIndex
Tags:
Self-assembling protein microarrays. Ramachandran et al. (2004). Science.
Source: Direct interaction with 119 interactions from iRefIndex
A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein. Goudreault et al. (2009). Mol Cell Proteomics.
Source: Direct interaction with 242 interactions from iRefIndex
Tags:
A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. Sato et al. (2004). Mol Cell.
Source: Direct interaction with 235 interactions from iRefIndex
Tags:
Large-scale structural analysis of the classical human protein tyrosine phosphatome. Barr et al. (2009). Cell.
Source: Direct interaction with 177 interactions from iRefIndex
Source: Direct interaction with 385 interactions from iRefIndex
A quantitative protein interaction network for the ErbB receptors using protein microarrays. Jones et al. (2006). Nature.
Source: Direct interaction with 139 interactions from iRefIndex
Tags:
Defining the human deubiquitinating enzyme interaction landscape. Sowa et al. (2009). Cell.
Note: One of 2 datasets produced from this publication.
Source: Direct interaction with 1,511 interactions from BioGRID
Source: Direct interaction with 41,955 interactions from iRefIndex
Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2. Cannavo et al. (2007). J Biol Chem.
Source: Direct interaction with 109 interactions from iRefIndex
Tags:
Source: Direct interaction with 28,821 interactions from BioGRID
Source: Direct interaction with 12,700 interactions from iRefIndex
Source: Direct interaction with 5,310 interactions from iRefIndex
Source: Direct interaction with 637 interactions from iRefIndex
Source: Direct interaction with 21,448 interactions from iRefIndex
RNA and RNA binding proteins participate in early stages of cell spreading through spreading initiation centers. de Hoog et al. (2004). Cell.
Source: Direct interaction with 220 interactions from iRefIndex
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. Svendsen et al. (2009). Cell.
Source: Direct interaction with 233 interactions from iRefIndex
Tags:
Source: Direct interaction with 13,341 interactions from iRefIndex
An integrated workflow for charting the human interaction proteome: insights into the PP2A system. Glatter et al. (2009). Mol Syst Biol.
Source: Direct interaction with 307 interactions from iRefIndex
Tags:
High-throughput mapping of a dynamic signaling network in mammalian cells. Barrios-Rodiles et al. (2005). Science.
Source: Direct interaction with 547 interactions from iRefIndex
Tags:
Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi. Chen et al. (2009). Proc Natl Acad Sci U S A.
Note: I2D predictions of protein protein interactions using Chen-Pawson-2009 Mus musculus data
Source: Direct interaction with 30 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 567 interactions from I2D
BioGRID: a general repository for interaction datasets. Stark et al. (2006). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using BioGRID Saccharomyces cerevisiae data
Source: Direct interaction with 13,434 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 1,196 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 15 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 3,001 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 16,074 interactions from I2D
A gene-coexpression network for global discovery of conserved genetic modules. Stuart et al. (2003). Science.
Source: 24,952 interactions from supplementary material
Tags:
High-quality binary protein interaction map of the yeast interactome network. Yu et al. (2008). Science.
Note: I2D predictions of protein protein interactions using Yu Gold Standard Saccharomyces cerevisiae data
Source: Direct interaction with 386 interactions from I2D
Tags:
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Rattus norvegicus data
Source: Direct interaction with 1,054 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Mus musculus data
Source: Direct interaction with 977 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Rattus norvegicus data
Source: Direct interaction with 574 interactions from I2D
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Mus musculus data
Source: Direct interaction with 3,422 interactions from I2D
BioGRID: a general repository for interaction datasets. Stark et al. (2006). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using BioGRID Mus musculus data
Source: Direct interaction with 288 interactions from I2D
Ontological visualization of protein-protein interactions. Drabkin et al. (2005). BMC Bioinformatics.
Note: I2D predictions of protein protein interactions using MGI Mus musculus data
Source: Direct interaction with 724 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 103 interactions from I2D
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Drosophila melanogaster data
Source: Direct interaction with 3,920 interactions from I2D
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Rattus norvegicus data
Source: Direct interaction with 556 interactions from I2D
Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Tewari et al. (2004). Mol Cell.
Note: I2D predictions of protein protein interactions usingTewari-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 18 interactions from I2D
Tags:
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Saccharomyces cerevisiae data
Source: Direct interaction with 1,543 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Caenorhabditis elegans data
Source: Direct interaction with 1,166 interactions from I2D
InnateDB: facilitating systems-level analyses of the mammalian innate immune response. Lynn et al. (2008). Mol Syst Biol.
Note: I2D predictions of protein protein interactions using INNATEDB Mus musculus data
Source: Direct interaction with 1,455 interactions from I2D
Tags:
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Caenorhabditis elegans data
Source: Direct interaction with 911 interactions from I2D
An in vivo map of the yeast protein interactome. Tarassov et al. (2008). Science.
Note: I2D predictions of protein protein interactions using Tarassov-Michnick-2008 Saccharomyces cerevisiae data
Source: Direct interaction with 441 interactions from I2D
Tags:
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Krogan et al. (2006). Nature.
Note: I2D predictions of protein protein interactions using Krogan-Greenblatt-2006 Saccharomyces cerevisiae data
Source: Direct interaction with 1,794 interactions from I2D
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Mus musculus data
Source: Direct interaction with 1,198 interactions from I2D
Source: Pearson correlation with 530,357 interactions from Pfam
Source: Pearson correlation with 488,822 interactions from InterPro
monoamine oxidase A [Source:HGNC Symbol;Acc:6833]
Functions:
Synonyms: ENSG00000189221; ENSP00000340684; ENSP00000440846; 4128; MAOA; NP_000231; NM_000240; AOFA_HUMAN; P21397;
More at Entrez
EPH receptor B3 [Source:HGNC Symbol;Acc:3394]
Functions:
Synonyms: ENSG00000182580; ENSP00000332118; 2049; EPHB3; NP_004434; NM_004443; ETK2; HEK2; TYRO6; EPHB3_HUMAN; P54753;
More at Entrez
peroxisomal biogenesis factor 11 alpha [Source:HGNC Symbol;Acc:8852]
Functions:
Synonyms: ENSG00000166821; ENSP00000300056; ENSP00000453492; ENSP00000453552; ENSP00000453878; 8800; PEX11A; NP_003838; NM_003847; MGC119947; MGC138534; PEX11-ALPHA; O75192; PX11A_HUMAN;
More at Entrez
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) [Source:HGNC Symbol;Acc:5008]
Functions:
Synonyms: ENSG00000134240; ENSP00000358414; ENSP00000439495; 3158; HMGCS2; NP_001159579; NP_005509; NM_001166107; NM_005518; HMCS2_HUMAN; P54868;
More at Entrez
betaine--homocysteine S-methyltransferase 2 [Source:HGNC Symbol;Acc:1048]
Functions:
Synonyms: ENSG00000132840; ENSP00000255192; ENSP00000428640; ENSP00000430155; ENSP00000430278; 23743; BHMT2; NP_001171476; NP_060084; NM_001178005; NM_017614; BHMT2_HUMAN; Q9H2M3;
More at Entrez
sodium channel, nonvoltage-gated 1, beta [Source:HGNC Symbol;Acc:10600]
Functions:
Synonyms: ENSG00000168447; ENSP00000302874; ENSP00000345751; 6338; SCNN1B; NP_000327; NM_000336; BESC1; ENaCb; ENaCbeta; SCNEB; P51168; SCNNB_HUMAN;
More at Entrez
monoamine oxidase B [Source:HGNC Symbol;Acc:6834]
Functions:
Synonyms: ENSG00000069535; ENSP00000367309; ENSP00000431416; ENSP00000441613; ENSP00000442240; 4129; MAOB; NP_000889; NM_000898; AOFB_HUMAN; P27338;
More at Entrez
homogentisate 1,2-dioxygenase [Source:HGNC Symbol;Acc:4892]
Functions:
Synonyms: ENSG00000113924; ENSP00000283871; ENSP00000417977; ENSP00000419163; ENSP00000419560; ENSP00000419838; 3081; HGD; NP_000178; NM_000187; AKU; HGO; HGD_HUMAN; Q93099;
More at Entrez
abhydrolase domain containing 5 [Source:HGNC Symbol;Acc:21396]
Functions:
Synonyms: ENSG00000011198; ENSP00000013894; ENSP00000390849; ENSP00000391582; ENSP00000392159; ENSP00000412014; 51099; ABHD5; NP_057090; NM_016006; CGI-58; CGI58; IECN2; NCIE2; ABHD5_HUMAN; Q8WTS1;
More at Entrez
alcohol dehydrogenase 1B (class I), beta polypeptide [Source:HGNC Symbol;Acc:250]
Functions:
Synonyms: ENSG00000196616; ENSP00000306606; ENSP00000378351; ENSP00000411072; ENSP00000425998; 125; ADH1B; NP_000659; NM_000668; ADH2; ADH1B_HUMAN; ADH1G_HUMAN; P00325; P00326;
More at Entrez
phosphodiesterase 3B, cGMP-inhibited [Source:HGNC Symbol;Acc:8779]
Functions:
Synonyms: ENSG00000152270; ENSP00000282096; ENSP00000388644; 5140; PDE3B; NP_000913; NM_000922; cGIPDE1; HcGIP1; PDE3B_HUMAN; Q13370;
More at Entrez
dopa decarboxylase (aromatic L-amino acid decarboxylase) [Source:HGNC Symbol;Acc:2719]
Functions:
Synonyms: ENSG00000132437; ENSP00000350616; ENSP00000370371; ENSP00000389422; ENSP00000393724; ENSP00000394094; ENSP00000395069; ENSP00000399184; ENSP00000403644; ENSP00000408626; 1644; DDC; NP_000781; NP_001076440; NP_001229815; NP_001229816; NP_001229817; NP_001229818; NP_001229819; NM_000790; NM_001082971; NM_001242886; NM_001242887; NM_001242888; NM_001242889; NM_001242890; AADC; DDC_HUMAN; P20711;
More at Entrez
frizzled family receptor 5 [Source:HGNC Symbol;Acc:4043]
Functions:
Synonyms: ENSG00000163251; ENSP00000354607; 7855; FZD5; NP_003459; NM_003468; NM_030804; C2orf31; DKFZP434E2135; HFZ5; FZD5_HUMAN; Q13467;
More at Entrez
UL16 binding protein 3 [Source:HGNC Symbol;Acc:14895]
Functions:
Synonyms: ENSG00000131019; ENSP00000253335; ENSP00000356308; ENSP00000382709; ENSP00000403562; 79465; ULBP3; NP_078794; NM_024518; RAET1N; N2DL3_HUMAN; Q9BZM4;
More at Entrez
flavin containing monooxygenase 5 [Source:HGNC Symbol;Acc:3773]
Functions:
Synonyms: ENSG00000131781; ENSP00000254090; ENSP00000358277; ENSP00000416011; ENSP00000432569; ENSP00000433742; ENSP00000436429; 2330; FMO5; NP_001138301; NP_001138302; NP_001452; NM_001144829; NM_001144830; NM_001461; FMO5_HUMAN; P49326;
More at Entrez
N-myc downstream regulated 1 [Source:HGNC Symbol;Acc:7679]
Functions:
Synonyms: ENSG00000104419; ENSP00000319977; ENSP00000347028; ENSP00000404854; ENSP00000427894; ENSP00000428345; ENSP00000428384; ENSP00000428802; ENSP00000428991; ENSP00000429007; ENSP00000429172; ENSP00000429272; ENSP00000429380; ENSP00000429524; ENSP00000429840; ENSP00000429994; ENSP00000430171; ENSP00000431057; ENSP00000437443; ENSP00000437892; ENSP00000440422; 10397; NDRG1; NP_001128714; NP_006087; NM_001135242; NM_006096; CAP43; CMT4D; GC4; HMSNL; NMSL; PROXY1; RIT42; RTP; TARG1; TDD5; NDRG1_HUMAN; Q92597;
More at Entrez
coagulation factor III (thromboplastin, tissue factor) [Source:HGNC Symbol;Acc:3541]
Functions:
Synonyms: ENSG00000117525; ENSP00000334145; ENSP00000359226; 2152; F3; NP_001171567; NP_001984; NM_001178096; NM_001993; CD142; TFA; P13726; TF_HUMAN;
More at Entrez
selenium binding protein 1 [Source:HGNC Symbol;Acc:10719]
Functions:
Synonyms: ENSG00000143416; ENSP00000357861; ENSP00000390433; ENSP00000395637; ENSP00000396209; ENSP00000397261; ENSP00000400841; ENSP00000402531; ENSP00000406222; ENSP00000408263; ENSP00000412816; ENSP00000413960; ENSP00000416206; 8991; SELENBP1; NP_003935; NM_003944; hSBP; LPSB; SBP56; SP56; Q13228; SBP1_HUMAN;
More at Entrez
heat-responsive protein 12 [Source:HGNC Symbol;Acc:16897]
Functions:
Synonyms: ENSG00000132541; ENSP00000254878; ENSP00000428596; ENSP00000429321; ENSP00000429536; ENSP00000430482; 10247; HRSP12; NP_005827; NM_005836; P14.5; UK114; P52758; UK114_HUMAN;
More at Entrez
chromosome 12 open reading frame 62 [Source:HGNC Symbol;Acc:28216]
Functions:
Synonyms: ENSG00000178449; ENSP00000326052; ENSP00000446524; ENSP00000447776; ENSP00000450331; 84987; C12orf62; NP_116290; NM_032901; MGC14288; CL062_HUMAN; Q96I36;
More at Entrez
CD59 molecule, complement regulatory protein [Source:HGNC Symbol;Acc:1689]
Functions:
Synonyms: ENSG00000085063; ENSP00000340210; ENSP00000379191; ENSP00000402425; ENSP00000403511; ENSP00000404822; ENSP00000410182; ENSP00000432362; ENSP00000432942; ENSP00000434617; ENSP00000435179; ENSP00000436497; ENSP00000436737; ENSP00000437122; 966; CD59; NP_000602; NP_001120695; NP_001120697; NP_001120698; NP_001120699; NP_976074; NP_976075; NP_976076; NM_000611; NM_001127223; NM_001127225; NM_001127226; NM_001127227; NM_203329; NM_203330; NM_203331; 16.3A5; 1F5; EJ16; EJ30; EL32; G344; HRF-20; HRF20; MAC-IP; MACIF; MEM43; MIC11; MIN1; MIN2; MIN3; MIRL; MSK21; p18-20; CD59_HUMAN; P13987;
More at Entrez
| query genes | n/a | 1 / 1 |
| oxidoreductase activity, acting on the CH-NH2 group of donors | 9.69E-1 | 2 / 10 |
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