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Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number. Wang et al. (2006). Cancer Res.
Source: Pearson correlation with 231,830 interactions from GEO
Tags:
Multiclass cancer diagnosis using tumor gene expression signatures. Ramaswamy et al. (2001). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 226,615 interactions from supplementary material
Tags:
Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia. Radtke et al. (2009). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 377,767 interactions from GEO
Tags:
Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis. Gobble et al. (2011). Cancer Res.
Source: Pearson correlation with 449,507 interactions from GEO
Tags:
Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia. Kang et al. (2010). Blood.
Source: Pearson correlation with 549,783 interactions from GEO
Tags:
A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. Hummel et al. (2006). N Engl J Med.
Source: Pearson correlation with 466,765 interactions from GEO
Tags:
Gene signatures of progression and metastasis in renal cell cancer. Jones et al. (2005). Clin Cancer Res.
Source: Pearson correlation with 365,428 interactions from GEO
Tags:
Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Bild et al. (2006). Nature.
Note: One of 3 datasets produced from this publication.
Source: Pearson correlation with 254,105 interactions from GEO
Tags:
Regional variation in gene expression in the healthy colon is dysregulated in ulcerative colitis. Noble et al. (2008). Gut.
Source: Pearson correlation with 603,016 interactions from GEO
The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle. Wu et al. (2007). Endocrine.
Source: Pearson correlation with 223,988 interactions from GEO
Tags:
Gene expression analysis of soft tissue sarcomas: characterization and reclassification of malignant fibrous histiocytoma. Nakayama et al. (2007). Mod Pathol.
Source: Pearson correlation with 361,398 interactions from GEO
Tags:
Tumor cell gene expression changes following short-term in vivo exposure to single agent chemotherapeutics are related to survival in multiple myeloma. Burington et al. (2008). Clin Cancer Res.
Source: Pearson correlation with 266,464 interactions from GEO
Tags:
Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells. Burczynski et al. (2006). J Mol Diagn.
Source: Pearson correlation with 419,356 interactions from GEO
Transcriptome signature of resistance exercise adaptations: mixed muscle and fiber type specific profiles in young and old adults. Raue et al. (2012). J Appl Physiol.
Source: Pearson correlation with 483,849 interactions from GEO
Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage. Rieger et al. (2004). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 220,846 interactions from GEO
Tags:
Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment. Arijs et al. (2009). PLoS One.
Source: Pearson correlation with 570,210 interactions from GEO
Tags:
Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers. Peng et al. (2009). BMC Genomics.
Source: Pearson correlation with 349,954 interactions from GEO
Tags:
Gene expression changes in the course of normal brain aging are sexually dimorphic. Berchtold et al. (2008). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 507,933 interactions from GEO
Tags:
Gene expression profiling and response signatures associated with differential responses to infliximab treatment in ulcerative colitis. Toedter et al. (2011). Am J Gastroenterol.
Source: Pearson correlation with 572,082 interactions from GEO
Tags:
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Perou et al. (1999). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 50,804 interactions from supplementary material
Tags:
Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays. Johnson et al. (2003). Science.
Source: Pearson correlation with 426,934 interactions from GEO
Tags:
A comprehensive transcript index of the human genome generated using microarrays and computational approaches. Schadt et al. (2004). Genome Biol.
Note: Predicted transcript array
Source: Pearson correlation with 60,454 interactions from GEO
Source: Direct interaction with 171 interactions from iRefIndex
Source: Direct interaction with 345 interactions from BioGRID
A human functional protein interaction network and its application to cancer data analysis. Wu et al. (2010). Genome Biol.
Source: 78,448 interactions from supplementary material
Tags:
Source: Direct interaction with 24,924 interactions from Pathway Commons
Source: Direct interaction with 937 interactions from Pathway Commons
Source: Direct interaction with 10,118 interactions from Pathway Commons
Source: Direct interaction with 598 interactions from Pathway Commons
Source: Direct interaction with 685 interactions from Pathway Commons
Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. Behzadnia et al. (2007). EMBO J.
Source: Direct interaction with 101 interactions from iRefIndex
Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. Kneissl et al. (2003). J Mol Biol.
Source: Direct interaction with 83 interactions from iRefIndex
Tags:
Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions. McFarland et al. (2008). Mol Cell Proteomics.
Source: Direct interaction with 152 interactions from iRefIndex
Tags:
Systematic analysis of human protein complexes identifies chromosome segregation proteins. Hutchins et al. (2010). Science.
Source: Direct interaction with 141 interactions from iRefIndex
Tags:
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Jeronimo et al. (2007). Mol Cell.
Source: Direct interaction with 660 interactions from iRefIndex
Tags:
Self-assembling protein microarrays. Ramachandran et al. (2004). Science.
Source: Direct interaction with 119 interactions from iRefIndex
A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein. Goudreault et al. (2009). Mol Cell Proteomics.
Source: Direct interaction with 242 interactions from iRefIndex
Tags:
A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. Sato et al. (2004). Mol Cell.
Source: Direct interaction with 235 interactions from iRefIndex
Tags:
Large-scale structural analysis of the classical human protein tyrosine phosphatome. Barr et al. (2009). Cell.
Source: Direct interaction with 177 interactions from iRefIndex
Source: Direct interaction with 385 interactions from iRefIndex
A quantitative protein interaction network for the ErbB receptors using protein microarrays. Jones et al. (2006). Nature.
Source: Direct interaction with 139 interactions from iRefIndex
Tags:
Defining the human deubiquitinating enzyme interaction landscape. Sowa et al. (2009). Cell.
Note: One of 2 datasets produced from this publication.
Source: Direct interaction with 1,511 interactions from BioGRID
Source: Direct interaction with 41,955 interactions from iRefIndex
Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2. Cannavo et al. (2007). J Biol Chem.
Source: Direct interaction with 109 interactions from iRefIndex
Tags:
Source: Direct interaction with 28,821 interactions from BioGRID
Source: Direct interaction with 12,700 interactions from iRefIndex
Source: Direct interaction with 5,310 interactions from iRefIndex
Source: Direct interaction with 637 interactions from iRefIndex
Source: Direct interaction with 21,448 interactions from iRefIndex
RNA and RNA binding proteins participate in early stages of cell spreading through spreading initiation centers. de Hoog et al. (2004). Cell.
Source: Direct interaction with 220 interactions from iRefIndex
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. Svendsen et al. (2009). Cell.
Source: Direct interaction with 233 interactions from iRefIndex
Tags:
Source: Direct interaction with 13,341 interactions from iRefIndex
An integrated workflow for charting the human interaction proteome: insights into the PP2A system. Glatter et al. (2009). Mol Syst Biol.
Source: Direct interaction with 307 interactions from iRefIndex
Tags:
High-throughput mapping of a dynamic signaling network in mammalian cells. Barrios-Rodiles et al. (2005). Science.
Source: Direct interaction with 547 interactions from iRefIndex
Tags:
Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi. Chen et al. (2009). Proc Natl Acad Sci U S A.
Note: I2D predictions of protein protein interactions using Chen-Pawson-2009 Mus musculus data
Source: Direct interaction with 30 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 567 interactions from I2D
BioGRID: a general repository for interaction datasets. Stark et al. (2006). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using BioGRID Saccharomyces cerevisiae data
Source: Direct interaction with 13,434 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 1,196 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 15 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 3,001 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 16,074 interactions from I2D
A gene-coexpression network for global discovery of conserved genetic modules. Stuart et al. (2003). Science.
Source: 24,952 interactions from supplementary material
Tags:
High-quality binary protein interaction map of the yeast interactome network. Yu et al. (2008). Science.
Note: I2D predictions of protein protein interactions using Yu Gold Standard Saccharomyces cerevisiae data
Source: Direct interaction with 386 interactions from I2D
Tags:
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Rattus norvegicus data
Source: Direct interaction with 1,054 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Mus musculus data
Source: Direct interaction with 977 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Rattus norvegicus data
Source: Direct interaction with 574 interactions from I2D
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Mus musculus data
Source: Direct interaction with 3,422 interactions from I2D
BioGRID: a general repository for interaction datasets. Stark et al. (2006). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using BioGRID Mus musculus data
Source: Direct interaction with 288 interactions from I2D
Ontological visualization of protein-protein interactions. Drabkin et al. (2005). BMC Bioinformatics.
Note: I2D predictions of protein protein interactions using MGI Mus musculus data
Source: Direct interaction with 724 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 103 interactions from I2D
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Drosophila melanogaster data
Source: Direct interaction with 3,920 interactions from I2D
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Rattus norvegicus data
Source: Direct interaction with 556 interactions from I2D
Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Tewari et al. (2004). Mol Cell.
Note: I2D predictions of protein protein interactions usingTewari-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 18 interactions from I2D
Tags:
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Saccharomyces cerevisiae data
Source: Direct interaction with 1,543 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Caenorhabditis elegans data
Source: Direct interaction with 1,166 interactions from I2D
InnateDB: facilitating systems-level analyses of the mammalian innate immune response. Lynn et al. (2008). Mol Syst Biol.
Note: I2D predictions of protein protein interactions using INNATEDB Mus musculus data
Source: Direct interaction with 1,455 interactions from I2D
Tags:
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Caenorhabditis elegans data
Source: Direct interaction with 911 interactions from I2D
An in vivo map of the yeast protein interactome. Tarassov et al. (2008). Science.
Note: I2D predictions of protein protein interactions using Tarassov-Michnick-2008 Saccharomyces cerevisiae data
Source: Direct interaction with 441 interactions from I2D
Tags:
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Krogan et al. (2006). Nature.
Note: I2D predictions of protein protein interactions using Krogan-Greenblatt-2006 Saccharomyces cerevisiae data
Source: Direct interaction with 1,794 interactions from I2D
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Mus musculus data
Source: Direct interaction with 1,198 interactions from I2D
Source: Pearson correlation with 530,357 interactions from Pfam
Source: Pearson correlation with 488,822 interactions from InterPro
phospholipase C, beta 2 [Source:HGNC Symbol;Acc:9055]
Functions:
Synonyms: ENSG00000137841; ENSP00000260402; ENSP00000411991; ENSP00000444652; ENSP00000452642; ENSP00000452916; ENSP00000453975; ENSP00000454025; 5330; PLCB2; NP_004564; NM_004573; FLJ38135; PLCB2_HUMAN; Q00722;
More at Entrez
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) [Source:HGNC Symbol;Acc:11778]
Functions:
Synonyms: ENSG00000198959; ENSP00000355330; ENSP00000362502; ENSP00000387642; ENSP00000437479; ENSP00000444701; 7052; TGM2; NP_004604; NP_945189; NM_004613; NM_198951; G-ALPHA-h; GNAH; TG2; TGC; P21980; TGM2_HUMAN;
More at Entrez
sphingosine-1-phosphate receptor 1 [Source:HGNC Symbol;Acc:3165]
Functions:
Synonyms: ENSG00000170989; ENSP00000305416; ENSP00000413066; 1901; S1PR1; NP_001391; NM_001400; CD363; CHEDG1; D1S3362; EDG-1; S1P1; P21453; S1PR1_HUMAN;
More at Entrez
TBC1 domain family, member 15 [Source:HGNC Symbol;Acc:25694]
Functions:
Synonyms: ENSG00000121749; ENSP00000318262; ENSP00000376986; ENSP00000417308; ENSP00000418091; ENSP00000418467; ENSP00000419365; ENSP00000420190; ENSP00000420678; ENSP00000448182; ENSP00000449643; 64786; TBC1D15; NP_001139685; NP_001139686; NP_073608; NM_001146213; NM_001146214; NM_022771; NR_027449; DKFZp761D0223; FLJ12085; RAB7-GAP; Q8TC07; TBC15_HUMAN;
More at Entrez
endothelin receptor type B [Source:HGNC Symbol;Acc:3180]
Functions:
Synonyms: ENSG00000136160; ENSP00000335311; ENSP00000366416; ENSP00000403401; 1910; EDNRB; NP_000106; NP_001116131; NP_001188326; NP_003982; NM_000115; NM_001122659; NM_001201397; NM_003991; ABCDS; ET-B; ET-BR; ETB; ETBR; ETRB; HSCR; HSCR2; WS4A; EDNRB_HUMAN; P24530;
More at Entrez
regulator of G-protein signaling 17 [Source:HGNC Symbol;Acc:14088]
Functions:
Synonyms: ENSG00000091844; ENSP00000206262; ENSP00000356194; 26575; RGS17; NP_036551; NM_012419; hRGS17; RGS-17; RGSZ2; Q9UGC6; RGS17_HUMAN;
More at Entrez
regulator of G-protein signaling 4 [Source:HGNC Symbol;Acc:10000]
Functions:
Synonyms: ENSG00000117152; ENSP00000356882; ENSP00000356884; ENSP00000356885; ENSP00000397181; ENSP00000432194; ENSP00000433261; ENSP00000436106; 5999; RGS4; NP_001095915; NP_001106851; NP_001106852; NP_005604; NM_001102445; NM_001113380; NM_001113381; NM_005613; P49798; RGS4_HUMAN;
More at Entrez
regulator of G-protein signaling 13 [Source:HGNC Symbol;Acc:9995]
Functions:
Synonyms: ENSG00000127074; ENSP00000375853; ENSP00000442837; 6003; RGS13; NP_002918; NP_658912; NM_002927; NM_144766; O14921; RGS13_HUMAN;
More at Entrez
phosphoinositide-3-kinase, regulatory subunit 5 [Source:HGNC Symbol;Acc:30035]
Functions:
Synonyms: ENSG00000141506; ENSP00000269300; ENSP00000392812; 23533; PIK3R5; NP_001136105; NP_001238780; NP_001238781; NP_001238782; NP_001238784; NP_055123; NM_001142633; NM_001251851; NM_001251852; NM_001251853; NM_001251855; NM_014308; F730038I15Rik; FOAP-2; p101; P101-PI3K; PI3R5_HUMAN; Q8WYR1;
More at Entrez
calumenin [Source:HGNC Symbol;Acc:1458]
Functions:
Synonyms: ENSG00000128595; ENSP00000249364; ENSP00000345931; ENSP00000408838; ENSP00000417973; ENSP00000420381; ENSP00000437551; ENSP00000438248; ENSP00000438994; ENSP00000439139; ENSP00000442110; ENSP00000444217; ENSP00000444963; 813; CALU; NP_001124146; NP_001186600; NP_001186601; NP_001186602; NP_001186603; NP_001210; NM_001130674; NM_001199671; NM_001199672; NM_001199673; NM_001199674; NM_001219; CALU_HUMAN; O43852;
More at Entrez
endothelin receptor type A [Source:HGNC Symbol;Acc:3179]
Functions:
Synonyms: ENSG00000151617; ENSP00000315011; ENSP00000341556; ENSP00000351359; ENSP00000377611; ENSP00000425281; ENSP00000425354; ENSP00000427259; 1909; EDNRA; NP_001159527; NP_001243212; NP_001948; NM_001166055; NM_001256283; NM_001957; NR_028596; NR_045958; ET-A; ETA; ETA-R; ETAR; ETRA; hET-AR; EDNRA_HUMAN; P25101;
More at Entrez
lymphoid-restricted membrane protein [Source:HGNC Symbol;Acc:6690]
Functions:
Synonyms: ENSG00000118308; ENSP00000346442; ENSP00000354805; ENSP00000444056; ENSP00000446496; ENSP00000448534; ENSP00000450246; ENSP00000450634; ENSP00000450767; ENSP00000451048; ENSP00000451159; ENSP00000451196; ENSP00000452116; 4033; LRMP; NP_001191055; NP_001191056; NP_006143; NM_001204126; NM_001204127; NM_006152; JAW1; LRMP_HUMAN; Q12912;
More at Entrez
transient receptor potential cation channel, subfamily M, member 7 [Source:HGNC Symbol;Acc:17994]
Functions:
Synonyms: ENSG00000092439; ENSP00000320239; ENSP00000452873; ENSP00000453277; ENSP00000454066; 54822; TRPM7; NP_060142; NM_017672; CHAK; CHAK1; LTRPC7; TRP-PLIK; Q96QT4; TRPM7_HUMAN;
More at Entrez
lamin B1 [Source:HGNC Symbol;Acc:6637]
Functions:
Synonyms: ENSG00000113368; ENSP00000261366; ENSP00000378761; 4001; LMNB1; NP_001185486; NP_005564; NM_001198557; NM_005573; ADLD; LMN; LMNB; LMNB1_HUMAN; P20700;
More at Entrez
mitogen-activated protein kinase kinase 6 [Source:HGNC Symbol;Acc:6846]
Functions:
Synonyms: ENSG00000108984; ENSP00000351997; 5608; MAP2K6; NP_002749; NM_002758; NM_031988; MAPKK6; MEK6; MKK6; PRKMK6; SAPKK-3; SAPKK3; MP2K6_HUMAN; P52564;
More at Entrez
potassium voltage-gated channel, shaker-related subfamily, beta member 2 [Source:HGNC Symbol;Acc:6229]
Functions:
Synonyms: ENSG00000069424; ENSP00000164247; ENSP00000318772; ENSP00000340824; ENSP00000367323; ENSP00000367327; ENSP00000367332; ENSP00000367337; ENSP00000367351; ENSP00000374283; ENSP00000389151; ENSP00000396167; ENSP00000398395; ENSP00000400285; 8514; KCNAB2; NP_001186789; NP_001186790; NP_001186791; NP_001186792; NP_003627; NP_742128; NM_001199860; NM_001199861; NM_001199862; NM_001199863; NM_003636; NM_172130; AKR6A5; HKvbeta2; HKvbeta2.1; HKvbeta2.2; KCNA2B; KV-BETA-2; KCAB2_HUMAN; Q13303;
More at Entrez
mitogen-activated protein kinase kinase 3 [Source:HGNC Symbol;Acc:6843]
Functions:
Synonyms: ENSG00000034152; ENSP00000319139; ENSP00000345083; ENSP00000355081; ENSP00000378869; ENSP00000431203; ENSP00000434068; ENSP00000436003; 5606; MAP2K3; NP_002747; NP_659731; NM_002756; NM_145109; NM_145110; MAPKK3; MEK3; MKK3; PRKMK3; SAPKK-2; SAPKK2; MP2K3_HUMAN; P46734;
More at Entrez
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) [Source:HGNC Symbol;Acc:9801]
Functions:
Synonyms: ENSG00000136238; ENSP00000258737; ENSP00000348461; 5879; RAC1; NP_008839; NP_061485; NM_006908; NM_018890; NM_198829; p21-Rac1; Rac-1; TC-25; P63000; RAC1_HUMAN;
More at Entrez
Rho GTPase activating protein 4 [Source:HGNC Symbol;Acc:674]
Functions:
Synonyms: ENSG00000089820; ENSP00000203786; ENSP00000359033; ENSP00000359045; ENSP00000377322; ENSP00000385042; ENSP00000397533; ENSP00000398019; ENSP00000398259; ENSP00000408656; ENSP00000411712; ENSP00000412437; ENSP00000413782; ENSP00000444169; 393; ARHGAP4; NP_001158213; NP_001657; NM_001164741; NM_001666; KIAA0131; RGC1; RhoGAP4; SrGAP4; P98171; RHG04_HUMAN;
More at Entrez
signal-induced proliferation-associated 1 [Source:HGNC Symbol;Acc:10885]
Functions:
Synonyms: ENSG00000213445; ENSP00000377771; ENSP00000377774; ENSP00000433686; ENSP00000434362; ENSP00000436269; ENSP00000436683; 6494; SIPA1; NP_006738; NP_694985; NM_006747; NM_153253; Q96FS4; SIPA1_HUMAN;
More at Entrez
Rho guanine nucleotide exchange factor (GEF) 1 [Source:HGNC Symbol;Acc:681]
Functions:
Synonyms: ENSG00000076928; ENSP00000323044; ENSP00000337261; ENSP00000344429; ENSP00000346532; ENSP00000367394; 9138; ARHGEF1; NP_004697; NP_945328; NP_945353; NM_004706; NM_198977; NM_199002; GEF1; LBCL2; LSC; P115-RHOGEF; SUB1.5; ARHG1_HUMAN; Q92888;
More at Entrez
| query genes | n/a | 1 / 1 |
| regulation of nucleotide metabolic process | 6.63E-6 | 8 / 288 |
| GTPase activator activity | 6.63E-6 | 6 / 97 |
| positive regulation of GTPase activity | 4.08E-5 | 6 / 140 |
| regulation of GTPase activity | 7.56E-5 | 6 / 167 |
| regulation of GTP catabolic process | 7.56E-5 | 6 / 169 |
| regulation of purine nucleotide catabolic process | 1.12E-4 | 6 / 191 |
| regulation of nucleotide catabolic process | 1.12E-4 | 6 / 191 |
| GTPase regulator activity | 1.14E-4 | 6 / 196 |
| nucleoside-triphosphatase regulator activity | 1.22E-4 | 6 / 202 |
| enzyme activator activity | 1.72E-4 | 6 / 218 |
| regulation of Ras protein signal transduction | 2.22E-2 | 4 / 136 |
| Rho protein signal transduction | 2.78E-2 | 3 / 47 |
| Ras GTPase activator activity | 3.49E-2 | 3 / 52 |
3.1.1
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