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Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number. Wang et al. (2006). Cancer Res.
Source: Pearson correlation with 231,830 interactions from GEO
Tags:
Multiclass cancer diagnosis using tumor gene expression signatures. Ramaswamy et al. (2001). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 226,615 interactions from supplementary material
Tags:
Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia. Radtke et al. (2009). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 377,767 interactions from GEO
Tags:
Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis. Gobble et al. (2011). Cancer Res.
Source: Pearson correlation with 449,507 interactions from GEO
Tags:
Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia. Kang et al. (2010). Blood.
Source: Pearson correlation with 549,783 interactions from GEO
Tags:
A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. Hummel et al. (2006). N Engl J Med.
Source: Pearson correlation with 466,765 interactions from GEO
Tags:
Gene signatures of progression and metastasis in renal cell cancer. Jones et al. (2005). Clin Cancer Res.
Source: Pearson correlation with 365,428 interactions from GEO
Tags:
Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Bild et al. (2006). Nature.
Note: One of 3 datasets produced from this publication.
Source: Pearson correlation with 254,105 interactions from GEO
Tags:
Regional variation in gene expression in the healthy colon is dysregulated in ulcerative colitis. Noble et al. (2008). Gut.
Source: Pearson correlation with 603,016 interactions from GEO
The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle. Wu et al. (2007). Endocrine.
Source: Pearson correlation with 223,988 interactions from GEO
Tags:
Gene expression analysis of soft tissue sarcomas: characterization and reclassification of malignant fibrous histiocytoma. Nakayama et al. (2007). Mod Pathol.
Source: Pearson correlation with 361,398 interactions from GEO
Tags:
Tumor cell gene expression changes following short-term in vivo exposure to single agent chemotherapeutics are related to survival in multiple myeloma. Burington et al. (2008). Clin Cancer Res.
Source: Pearson correlation with 266,464 interactions from GEO
Tags:
Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells. Burczynski et al. (2006). J Mol Diagn.
Source: Pearson correlation with 419,356 interactions from GEO
Transcriptome signature of resistance exercise adaptations: mixed muscle and fiber type specific profiles in young and old adults. Raue et al. (2012). J Appl Physiol.
Source: Pearson correlation with 483,849 interactions from GEO
Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage. Rieger et al. (2004). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 220,846 interactions from GEO
Tags:
Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment. Arijs et al. (2009). PLoS One.
Source: Pearson correlation with 570,210 interactions from GEO
Tags:
Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers. Peng et al. (2009). BMC Genomics.
Source: Pearson correlation with 349,954 interactions from GEO
Tags:
Gene expression changes in the course of normal brain aging are sexually dimorphic. Berchtold et al. (2008). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 507,933 interactions from GEO
Tags:
Gene expression profiling and response signatures associated with differential responses to infliximab treatment in ulcerative colitis. Toedter et al. (2011). Am J Gastroenterol.
Source: Pearson correlation with 572,082 interactions from GEO
Tags:
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Perou et al. (1999). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 50,804 interactions from supplementary material
Tags:
Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays. Johnson et al. (2003). Science.
Source: Pearson correlation with 426,934 interactions from GEO
Tags:
A comprehensive transcript index of the human genome generated using microarrays and computational approaches. Schadt et al. (2004). Genome Biol.
Note: Predicted transcript array
Source: Pearson correlation with 60,454 interactions from GEO
Source: Direct interaction with 171 interactions from iRefIndex
Source: Direct interaction with 345 interactions from BioGRID
A human functional protein interaction network and its application to cancer data analysis. Wu et al. (2010). Genome Biol.
Source: 78,448 interactions from supplementary material
Tags:
Source: Direct interaction with 24,924 interactions from Pathway Commons
Source: Direct interaction with 937 interactions from Pathway Commons
Source: Direct interaction with 10,118 interactions from Pathway Commons
Source: Direct interaction with 598 interactions from Pathway Commons
Source: Direct interaction with 685 interactions from Pathway Commons
Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. Behzadnia et al. (2007). EMBO J.
Source: Direct interaction with 101 interactions from iRefIndex
Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. Kneissl et al. (2003). J Mol Biol.
Source: Direct interaction with 83 interactions from iRefIndex
Tags:
Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions. McFarland et al. (2008). Mol Cell Proteomics.
Source: Direct interaction with 152 interactions from iRefIndex
Tags:
Systematic analysis of human protein complexes identifies chromosome segregation proteins. Hutchins et al. (2010). Science.
Source: Direct interaction with 141 interactions from iRefIndex
Tags:
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Jeronimo et al. (2007). Mol Cell.
Source: Direct interaction with 660 interactions from iRefIndex
Tags:
Self-assembling protein microarrays. Ramachandran et al. (2004). Science.
Source: Direct interaction with 119 interactions from iRefIndex
A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein. Goudreault et al. (2009). Mol Cell Proteomics.
Source: Direct interaction with 242 interactions from iRefIndex
Tags:
A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. Sato et al. (2004). Mol Cell.
Source: Direct interaction with 235 interactions from iRefIndex
Tags:
Large-scale structural analysis of the classical human protein tyrosine phosphatome. Barr et al. (2009). Cell.
Source: Direct interaction with 177 interactions from iRefIndex
Source: Direct interaction with 385 interactions from iRefIndex
A quantitative protein interaction network for the ErbB receptors using protein microarrays. Jones et al. (2006). Nature.
Source: Direct interaction with 139 interactions from iRefIndex
Tags:
Defining the human deubiquitinating enzyme interaction landscape. Sowa et al. (2009). Cell.
Note: One of 2 datasets produced from this publication.
Source: Direct interaction with 1,511 interactions from BioGRID
Source: Direct interaction with 41,955 interactions from iRefIndex
Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2. Cannavo et al. (2007). J Biol Chem.
Source: Direct interaction with 109 interactions from iRefIndex
Tags:
Source: Direct interaction with 28,821 interactions from BioGRID
Source: Direct interaction with 12,700 interactions from iRefIndex
Source: Direct interaction with 5,310 interactions from iRefIndex
Source: Direct interaction with 637 interactions from iRefIndex
Source: Direct interaction with 21,448 interactions from iRefIndex
RNA and RNA binding proteins participate in early stages of cell spreading through spreading initiation centers. de Hoog et al. (2004). Cell.
Source: Direct interaction with 220 interactions from iRefIndex
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. Svendsen et al. (2009). Cell.
Source: Direct interaction with 233 interactions from iRefIndex
Tags:
Source: Direct interaction with 13,341 interactions from iRefIndex
An integrated workflow for charting the human interaction proteome: insights into the PP2A system. Glatter et al. (2009). Mol Syst Biol.
Source: Direct interaction with 307 interactions from iRefIndex
Tags:
High-throughput mapping of a dynamic signaling network in mammalian cells. Barrios-Rodiles et al. (2005). Science.
Source: Direct interaction with 547 interactions from iRefIndex
Tags:
Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi. Chen et al. (2009). Proc Natl Acad Sci U S A.
Note: I2D predictions of protein protein interactions using Chen-Pawson-2009 Mus musculus data
Source: Direct interaction with 30 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 567 interactions from I2D
BioGRID: a general repository for interaction datasets. Stark et al. (2006). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using BioGRID Saccharomyces cerevisiae data
Source: Direct interaction with 13,434 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 1,196 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 15 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 3,001 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 16,074 interactions from I2D
A gene-coexpression network for global discovery of conserved genetic modules. Stuart et al. (2003). Science.
Source: 24,952 interactions from supplementary material
Tags:
High-quality binary protein interaction map of the yeast interactome network. Yu et al. (2008). Science.
Note: I2D predictions of protein protein interactions using Yu Gold Standard Saccharomyces cerevisiae data
Source: Direct interaction with 386 interactions from I2D
Tags:
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Rattus norvegicus data
Source: Direct interaction with 1,054 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Mus musculus data
Source: Direct interaction with 977 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Rattus norvegicus data
Source: Direct interaction with 574 interactions from I2D
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Mus musculus data
Source: Direct interaction with 3,422 interactions from I2D
BioGRID: a general repository for interaction datasets. Stark et al. (2006). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using BioGRID Mus musculus data
Source: Direct interaction with 288 interactions from I2D
Ontological visualization of protein-protein interactions. Drabkin et al. (2005). BMC Bioinformatics.
Note: I2D predictions of protein protein interactions using MGI Mus musculus data
Source: Direct interaction with 724 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 103 interactions from I2D
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Drosophila melanogaster data
Source: Direct interaction with 3,920 interactions from I2D
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Rattus norvegicus data
Source: Direct interaction with 556 interactions from I2D
Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Tewari et al. (2004). Mol Cell.
Note: I2D predictions of protein protein interactions usingTewari-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 18 interactions from I2D
Tags:
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Saccharomyces cerevisiae data
Source: Direct interaction with 1,543 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Caenorhabditis elegans data
Source: Direct interaction with 1,166 interactions from I2D
InnateDB: facilitating systems-level analyses of the mammalian innate immune response. Lynn et al. (2008). Mol Syst Biol.
Note: I2D predictions of protein protein interactions using INNATEDB Mus musculus data
Source: Direct interaction with 1,455 interactions from I2D
Tags:
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Caenorhabditis elegans data
Source: Direct interaction with 911 interactions from I2D
An in vivo map of the yeast protein interactome. Tarassov et al. (2008). Science.
Note: I2D predictions of protein protein interactions using Tarassov-Michnick-2008 Saccharomyces cerevisiae data
Source: Direct interaction with 441 interactions from I2D
Tags:
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Krogan et al. (2006). Nature.
Note: I2D predictions of protein protein interactions using Krogan-Greenblatt-2006 Saccharomyces cerevisiae data
Source: Direct interaction with 1,794 interactions from I2D
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Mus musculus data
Source: Direct interaction with 1,198 interactions from I2D
Source: Pearson correlation with 530,357 interactions from Pfam
Source: Pearson correlation with 488,822 interactions from InterPro
KIAA2013 [Source:HGNC Symbol;Acc:28513]
Functions:
Synonyms: ENSG00000116685; ENSP00000365756; ENSP00000365760; 90231; KIAA2013; NP_612355; NM_138346; MGC33867; RP5-1077B9.1; K2013_HUMAN; Q8IYS2;
More at Entrez
membrane-associated ring finger (C3HC4) 9 [Source:HGNC Symbol;Acc:25139]
Functions:
Synonyms: ENSG00000139266; ENSP00000266643; ENSP00000446758; 92979; MARCH9; NP_612405; NM_138396; FLJ36578; MARCH-IX; RNF179; MARH9_HUMAN; Q86YJ5;
More at Entrez
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) [Source:HGNC Symbol;Acc:4589]
Functions:
Synonyms: ENSG00000178719; ENSP00000314380; ENSP00000378507; ENSP00000431217; ENSP00000432095; ENSP00000432706; ENSP00000435901; ENSP00000436807; ENSP00000442314; 2907; GRINA; NP_000828; NP_001009184; NM_000837; NM_001009184; HNRGW; LFG1; NMDARA1; TMBIM3; GRINA_HUMAN; Q7Z429;
More at Entrez
chromosome 10 open reading frame 26 [Source:HGNC Symbol;Acc:23510]
Functions:
Synonyms: ENSG00000166272; ENSP00000358905; ENSP00000414721; 54838; C10orf26; NP_001077382; NP_060257; NM_001083913; NM_017787; FLJ20154; OPA1L; OPAL1; OPA1L_HUMAN; Q9NX94;
More at Entrez
leucine zipper-EF-hand containing transmembrane protein 1 [Source:HGNC Symbol;Acc:6556]
Functions:
Synonyms: ENSG00000168924; ENSP00000305653; ENSP00000411665; 3954; LETM1; NP_036450; NM_012318; LETM1_HUMAN; O95202;
More at Entrez
thyroid hormone receptor, alpha [Source:HGNC Symbol;Acc:11796]
Functions:
Synonyms: ENSG00000126351; ENSP00000264637; ENSP00000377679; ENSP00000395641; ENSP00000443972; 7067; THRA; NP_001177847; NP_001177848; NP_003241; NP_955366; NM_001190918; NM_001190919; NM_003250; NM_199334; AR7; c-ERBA-1; EAR-7.1/EAR-7.2; EAR7; ERB-T-1; ERBA; ERBA1; NR1A1; THRA2; THRA3; P10827; THA_HUMAN;
More at Entrez
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B [Source:HGNC Symbol;Acc:10730]
Functions:
Synonyms: ENSG00000185033; ENSP00000332204; ENSP00000368417; ENSP00000394720; ENSP00000452886; ENSP00000452957; ENSP00000453272; ENSP00000453484; ENSP00000453563; ENSP00000453705; ENSP00000453804; ENSP00000453866; ENSP00000453951; ENSP00000454068; 10509; SEMA4B; NP_064595; NP_945119; NM_020210; NM_198925; KIAA1745; MGC131831; SEMAC; SemC; Q9NPR2; SEM4B_HUMAN;
More at Entrez
insulin receptor [Source:HGNC Symbol;Acc:6091]
Functions:
Synonyms: ENSG00000171105; ENSP00000303830; ENSP00000342838; ENSP00000437589; 3643; INSR; NP_000199; NP_001073285; NM_000208; NM_001079817; CD220; HHF5; INSR_HUMAN; P06213;
More at Entrez
toll-interleukin 1 receptor (TIR) domain containing adaptor protein [Source:HGNC Symbol;Acc:17192]
Functions:
Synonyms: ENSG00000150455; ENSP00000279992; ENSP00000376445; ENSP00000376446; ENSP00000376447; ENSP00000436967; ENSP00000446213; 114609; TIRAP; NP_001034750; NP_683708; NM_001039661; NM_052887; NM_148910; BACTS1; wyatt; P58753; TIRAP_HUMAN;
More at Entrez
chromosome 1 open reading frame 122 [Source:HGNC Symbol;Acc:24789]
Functions:
Synonyms: ENSG00000197982; ENSP00000362133; ENSP00000362134; ENSP00000389807; ENSP00000434520; 127687; C1orf122; NP_001136198; NP_940848; NM_001142726; NM_198446; ALAESM; FLJ45459; CA122_HUMAN; Q6ZSJ8;
More at Entrez
solute carrier family 35, member A4 [Source:HGNC Symbol;Acc:20753]
Functions:
Synonyms: ENSG00000176087; ENSP00000327133; ENSP00000415133; ENSP00000424566; 113829; SLC35A4; NP_542401; NM_080670; Q96G79; S35A4_HUMAN;
More at Entrez
ATG9 autophagy related 9 homolog A (S. cerevisiae) [Source:HGNC Symbol;Acc:22408]
Functions:
Synonyms: ENSG00000198925; ENSP00000355173; ENSP00000379983; ENSP00000386482; ENSP00000386535; ENSP00000386710; ENSP00000390704; ENSP00000393708; ENSP00000394345; ENSP00000396404; ENSP00000398425; ENSP00000398528; ENSP00000400234; ENSP00000401530; ENSP00000404750; ENSP00000406785; ENSP00000409164; ENSP00000413569; ENSP00000416435; 79065; ATG9A; NP_001070666; NP_076990; NM_001077198; NM_024085; APG9L1; FLJ22169; mATG9; MGD3208; ATG9A_HUMAN; Q7Z3C6;
More at Entrez
zinc finger protein 592 [Source:HGNC Symbol;Acc:28986]
Functions:
Synonyms: ENSG00000166716; ENSP00000299927; ENSP00000452877; ENSP00000453491; 9640; ZNF592; NP_055445; NM_014630; CAMOS; KIAA0211; SCAR5; Q92610; ZN592_HUMAN;
More at Entrez
unc-51-like kinase 3 (C. elegans) [Source:HGNC Symbol;Acc:19703]
Functions:
Synonyms: ENSG00000140474; ENSP00000393658; ENSP00000400312; 25989; ULK3; NP_001092906; NM_001099436; NM_015518; DKFZP434C131; FLJ90566; Q6PHR2; ULK3_HUMAN;
More at Entrez
carboxylesterase 2 [Source:HGNC Symbol;Acc:1864]
Functions:
Synonyms: ENSG00000172831; ENSP00000317842; ENSP00000394452; 8824; CES2; NP_003860; NP_932327; NM_003869; NM_198061; NR_036684; CE-2; CES2A1; PCE-2; EST2_HUMAN; O00748;
More at Entrez
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 [Source:HGNC Symbol;Acc:24139]
Functions:
Synonyms: ENSG00000177191; ENSP00000312700; 374907; B3GNT8; NP_940942; NM_198540; B3GALT7; beta3Gn-T8; BGALT15; B3GN8_HUMAN; Q7Z7M8;
More at Entrez
abhydrolase domain containing 15 [Source:HGNC Symbol;Acc:26971]
Functions:
Synonyms: ENSG00000168792; ENSP00000302657; 116236; ABHD15; NP_937790; NM_198147; ABH15_HUMAN; Q6UXT9;
More at Entrez
receptor accessory protein 6 [Source:HGNC Symbol;Acc:30078]
Functions:
Synonyms: ENSG00000115255; ENSP00000233596; ENSP00000378861; ENSP00000378865; 92840; REEP6; NP_612402; NM_138393; C19orf32; DP1L1; FLJ25383; TB2L1; Q96HR9; REEP6_HUMAN;
More at Entrez
eukaryotic translation initiation factor 4E family member 2 [Source:HGNC Symbol;Acc:3293]
Functions:
Synonyms: ENSG00000135930; ENSP00000258416; ENSP00000386424; ENSP00000386876; ENSP00000386983; ENSP00000386996; ENSP00000387328; ENSP00000387336; ENSP00000389578; ENSP00000390904; 9470; EIF4E2; NP_004837; NM_004846; 4E-LP; 4EHP; EIF4EL3; IF4e; IF4E2_HUMAN; O60573;
More at Entrez
solute carrier family 2 (facilitated glucose transporter), member 6 [Source:HGNC Symbol;Acc:11011]
Functions:
Synonyms: ENSG00000160326; ENSP00000360964; ENSP00000360966; ENSP00000398004; ENSP00000405124; 11182; SLC2A6; NP_001138571; NP_060055; NM_001145099; NM_017585; GLUT6; HSA011372; GTR6_HUMAN; Q9UGQ3;
More at Entrez
uridine-cytidine kinase 1 [Source:HGNC Symbol;Acc:14859]
Functions:
Synonyms: ENSG00000130717; ENSP00000361282; ENSP00000361284; ENSP00000361285; ENSP00000361289; ENSP00000432363; 83549; UCK1; NP_001129426; NP_113620; NM_001135954; NM_031432; FLJ12255; URK1; Q9HA47; UCK1_HUMAN;
More at Entrez
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