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Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number. Wang et al. (2006). Cancer Res.
Source: Pearson correlation with 231,830 interactions from GEO
Tags:
Multiclass cancer diagnosis using tumor gene expression signatures. Ramaswamy et al. (2001). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 226,615 interactions from supplementary material
Tags:
Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia. Radtke et al. (2009). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 377,767 interactions from GEO
Tags:
Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis. Gobble et al. (2011). Cancer Res.
Source: Pearson correlation with 449,507 interactions from GEO
Tags:
Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia. Kang et al. (2010). Blood.
Source: Pearson correlation with 549,783 interactions from GEO
Tags:
A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. Hummel et al. (2006). N Engl J Med.
Source: Pearson correlation with 466,765 interactions from GEO
Tags:
Gene signatures of progression and metastasis in renal cell cancer. Jones et al. (2005). Clin Cancer Res.
Source: Pearson correlation with 365,428 interactions from GEO
Tags:
Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Bild et al. (2006). Nature.
Note: One of 3 datasets produced from this publication.
Source: Pearson correlation with 254,105 interactions from GEO
Tags:
Regional variation in gene expression in the healthy colon is dysregulated in ulcerative colitis. Noble et al. (2008). Gut.
Source: Pearson correlation with 603,016 interactions from GEO
The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle. Wu et al. (2007). Endocrine.
Source: Pearson correlation with 223,988 interactions from GEO
Tags:
Gene expression analysis of soft tissue sarcomas: characterization and reclassification of malignant fibrous histiocytoma. Nakayama et al. (2007). Mod Pathol.
Source: Pearson correlation with 361,398 interactions from GEO
Tags:
Tumor cell gene expression changes following short-term in vivo exposure to single agent chemotherapeutics are related to survival in multiple myeloma. Burington et al. (2008). Clin Cancer Res.
Source: Pearson correlation with 266,464 interactions from GEO
Tags:
Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells. Burczynski et al. (2006). J Mol Diagn.
Source: Pearson correlation with 419,356 interactions from GEO
Transcriptome signature of resistance exercise adaptations: mixed muscle and fiber type specific profiles in young and old adults. Raue et al. (2012). J Appl Physiol.
Source: Pearson correlation with 483,849 interactions from GEO
Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage. Rieger et al. (2004). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 220,846 interactions from GEO
Tags:
Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment. Arijs et al. (2009). PLoS One.
Source: Pearson correlation with 570,210 interactions from GEO
Tags:
Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers. Peng et al. (2009). BMC Genomics.
Source: Pearson correlation with 349,954 interactions from GEO
Tags:
Gene expression changes in the course of normal brain aging are sexually dimorphic. Berchtold et al. (2008). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 507,933 interactions from GEO
Tags:
Gene expression profiling and response signatures associated with differential responses to infliximab treatment in ulcerative colitis. Toedter et al. (2011). Am J Gastroenterol.
Source: Pearson correlation with 572,082 interactions from GEO
Tags:
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Perou et al. (1999). Proc Natl Acad Sci U S A.
Source: Pearson correlation with 50,804 interactions from supplementary material
Tags:
Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays. Johnson et al. (2003). Science.
Source: Pearson correlation with 426,934 interactions from GEO
Tags:
A comprehensive transcript index of the human genome generated using microarrays and computational approaches. Schadt et al. (2004). Genome Biol.
Note: Predicted transcript array
Source: Pearson correlation with 60,454 interactions from GEO
Source: Direct interaction with 171 interactions from iRefIndex
Source: Direct interaction with 345 interactions from BioGRID
A human functional protein interaction network and its application to cancer data analysis. Wu et al. (2010). Genome Biol.
Source: 78,448 interactions from supplementary material
Tags:
Source: Direct interaction with 24,924 interactions from Pathway Commons
Source: Direct interaction with 937 interactions from Pathway Commons
Source: Direct interaction with 10,118 interactions from Pathway Commons
Source: Direct interaction with 598 interactions from Pathway Commons
Source: Direct interaction with 685 interactions from Pathway Commons
Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. Behzadnia et al. (2007). EMBO J.
Source: Direct interaction with 101 interactions from iRefIndex
Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. Kneissl et al. (2003). J Mol Biol.
Source: Direct interaction with 83 interactions from iRefIndex
Tags:
Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions. McFarland et al. (2008). Mol Cell Proteomics.
Source: Direct interaction with 152 interactions from iRefIndex
Tags:
Systematic analysis of human protein complexes identifies chromosome segregation proteins. Hutchins et al. (2010). Science.
Source: Direct interaction with 141 interactions from iRefIndex
Tags:
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Jeronimo et al. (2007). Mol Cell.
Source: Direct interaction with 660 interactions from iRefIndex
Tags:
Self-assembling protein microarrays. Ramachandran et al. (2004). Science.
Source: Direct interaction with 119 interactions from iRefIndex
A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein. Goudreault et al. (2009). Mol Cell Proteomics.
Source: Direct interaction with 242 interactions from iRefIndex
Tags:
A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. Sato et al. (2004). Mol Cell.
Source: Direct interaction with 235 interactions from iRefIndex
Tags:
Large-scale structural analysis of the classical human protein tyrosine phosphatome. Barr et al. (2009). Cell.
Source: Direct interaction with 177 interactions from iRefIndex
Source: Direct interaction with 385 interactions from iRefIndex
A quantitative protein interaction network for the ErbB receptors using protein microarrays. Jones et al. (2006). Nature.
Source: Direct interaction with 139 interactions from iRefIndex
Tags:
Defining the human deubiquitinating enzyme interaction landscape. Sowa et al. (2009). Cell.
Note: One of 2 datasets produced from this publication.
Source: Direct interaction with 1,511 interactions from BioGRID
Source: Direct interaction with 41,955 interactions from iRefIndex
Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2. Cannavo et al. (2007). J Biol Chem.
Source: Direct interaction with 109 interactions from iRefIndex
Tags:
Source: Direct interaction with 28,821 interactions from BioGRID
Source: Direct interaction with 12,700 interactions from iRefIndex
Source: Direct interaction with 5,310 interactions from iRefIndex
Source: Direct interaction with 637 interactions from iRefIndex
Source: Direct interaction with 21,448 interactions from iRefIndex
RNA and RNA binding proteins participate in early stages of cell spreading through spreading initiation centers. de Hoog et al. (2004). Cell.
Source: Direct interaction with 220 interactions from iRefIndex
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. Svendsen et al. (2009). Cell.
Source: Direct interaction with 233 interactions from iRefIndex
Tags:
Source: Direct interaction with 13,341 interactions from iRefIndex
An integrated workflow for charting the human interaction proteome: insights into the PP2A system. Glatter et al. (2009). Mol Syst Biol.
Source: Direct interaction with 307 interactions from iRefIndex
Tags:
High-throughput mapping of a dynamic signaling network in mammalian cells. Barrios-Rodiles et al. (2005). Science.
Source: Direct interaction with 547 interactions from iRefIndex
Tags:
Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi. Chen et al. (2009). Proc Natl Acad Sci U S A.
Note: I2D predictions of protein protein interactions using Chen-Pawson-2009 Mus musculus data
Source: Direct interaction with 30 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 567 interactions from I2D
BioGRID: a general repository for interaction datasets. Stark et al. (2006). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using BioGRID Saccharomyces cerevisiae data
Source: Direct interaction with 13,434 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 1,196 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 15 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 3,001 interactions from I2D
Comparative assessment of large-scale data sets of protein-protein interactions. von Mering et al. (2002). Nature.
Note: I2D predictions of protein protein interactions using vonMering-Bork-2002 Saccharomyces cerevisiae data
Source: Direct interaction with 16,074 interactions from I2D
A gene-coexpression network for global discovery of conserved genetic modules. Stuart et al. (2003). Science.
Source: 24,952 interactions from supplementary material
Tags:
High-quality binary protein interaction map of the yeast interactome network. Yu et al. (2008). Science.
Note: I2D predictions of protein protein interactions using Yu Gold Standard Saccharomyces cerevisiae data
Source: Direct interaction with 386 interactions from I2D
Tags:
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Rattus norvegicus data
Source: Direct interaction with 1,054 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Mus musculus data
Source: Direct interaction with 977 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Rattus norvegicus data
Source: Direct interaction with 574 interactions from I2D
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Mus musculus data
Source: Direct interaction with 3,422 interactions from I2D
BioGRID: a general repository for interaction datasets. Stark et al. (2006). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using BioGRID Mus musculus data
Source: Direct interaction with 288 interactions from I2D
Ontological visualization of protein-protein interactions. Drabkin et al. (2005). BMC Bioinformatics.
Note: I2D predictions of protein protein interactions using MGI Mus musculus data
Source: Direct interaction with 724 interactions from I2D
A map of the interactome network of the metazoan C. elegans. Li et al. (2004). Science.
Note: I2D predictions of protein protein interactions using Li-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 103 interactions from I2D
The IntAct molecular interaction database in 2010. Aranda et al. (2010). Nucleic Acids Res.
Note: I2D predictions of protein protein interactions using IntAct Drosophila melanogaster data
Source: Direct interaction with 3,920 interactions from I2D
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Rattus norvegicus data
Source: Direct interaction with 556 interactions from I2D
Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Tewari et al. (2004). Mol Cell.
Note: I2D predictions of protein protein interactions usingTewari-Vidal-2004 Caenorhabditis elegans data
Source: Direct interaction with 18 interactions from I2D
Tags:
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Saccharomyces cerevisiae data
Source: Direct interaction with 1,543 interactions from I2D
MINT: a Molecular INTeraction database. Zanzoni et al. (2002). FEBS Lett.
Note: I2D predictions of protein protein interactions using MINT Caenorhabditis elegans data
Source: Direct interaction with 1,166 interactions from I2D
InnateDB: facilitating systems-level analyses of the mammalian innate immune response. Lynn et al. (2008). Mol Syst Biol.
Note: I2D predictions of protein protein interactions using INNATEDB Mus musculus data
Source: Direct interaction with 1,455 interactions from I2D
Tags:
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Caenorhabditis elegans data
Source: Direct interaction with 911 interactions from I2D
An in vivo map of the yeast protein interactome. Tarassov et al. (2008). Science.
Note: I2D predictions of protein protein interactions using Tarassov-Michnick-2008 Saccharomyces cerevisiae data
Source: Direct interaction with 441 interactions from I2D
Tags:
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Krogan et al. (2006). Nature.
Note: I2D predictions of protein protein interactions using Krogan-Greenblatt-2006 Saccharomyces cerevisiae data
Source: Direct interaction with 1,794 interactions from I2D
BIND--a data specification for storing and describing biomolecular interactions, molecular complexes and pathways. Bader et al. (2000). Bioinformatics.
Note: I2D predictions of protein protein interactions using BIND Mus musculus data
Source: Direct interaction with 1,198 interactions from I2D
Source: Pearson correlation with 530,357 interactions from Pfam
Source: Pearson correlation with 488,822 interactions from InterPro
leucine rich repeat and sterile alpha motif containing 1 [Source:HGNC Symbol;Acc:25135]
Functions:
Synonyms: ENSG00000148356; ENSP00000300417; ENSP00000322937; ENSP00000362419; ENSP00000362421; 90678; LRSAM1; NP_001005373; NP_001005374; NP_001177652; NP_612370; NM_001005373; NM_001005374; NM_001190723; NM_138361; FLJ31641; RIFLE; LRSM1_HUMAN; Q6UWE0;
More at Entrez
UEV and lactate/malate dehyrogenase domains [Source:HGNC Symbol;Acc:30866]
Functions:
Synonyms: ENSG00000151116; ENSP00000300038; ENSP00000323353; ENSP00000368697; ENSP00000379499; ENSP00000379500; ENSP00000437538; ENSP00000438779; ENSP00000441092; ENSP00000442974; 55293; UEVLD; NP_001035787; NP_060784; NM_001040697; NM_001040698; NM_018314; UEV3; Q8IX04; UEVLD_HUMAN;
More at Entrez
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B [Source:HGNC Symbol;Acc:7048]
Functions:
Synonyms: ENSG00000161013; ENSP00000292591; ENSP00000338487; ENSP00000427995; ENSP00000428764; ENSP00000428906; ENSP00000428960; ENSP00000430376; ENSP00000430721; ENSP00000430723; ENSP00000430964; ENSP00000431093; 11282; MGAT4B; NP_055090; NP_463459; NM_014275; NM_054013; GNT-IVB; MGT4B_HUMAN; Q9UQ53;
More at Entrez
myosin, light chain 2, regulatory, cardiac, slow [Source:HGNC Symbol;Acc:7583]
Functions:
Synonyms: ENSG00000111245; ENSP00000228841; ENSP00000447154; ENSP00000449490; 4633; MYL2; NP_000423; NM_000432; CMH10; MLRV_HUMAN; P10916;
More at Entrez
ubiquitin-conjugating enzyme E2, J1, U [Source:HGNC Symbol;Acc:17598]
Functions:
Synonyms: ENSG00000198833; ENSP00000441898; ENSP00000451261; 51465; UBE2J1; NP_057105; NM_016021; CGI-76; HSPC153; HSPC205; HSU93243; NCUBE-1; NCUBE1; UBC6; Q9Y385; UB2J1_HUMAN;
More at Entrez
tumor susceptibility gene 101 [Source:HGNC Symbol;Acc:15971]
Functions:
Synonyms: ENSG00000074319; ENSP00000251968; ENSP00000349721; ENSP00000438471; 7251; TSG101; NP_006283; NM_006292; TSG10; VPS23; Q99816; TS101_HUMAN;
More at Entrez
family with sequence similarity 178, member B [Source:HGNC Symbol;Acc:28036]
Functions:
Synonyms: ENSG00000168754; ENSP00000333553; ENSP00000377160; ENSP00000413245; ENSP00000429896; 51252; FAM178B; NP_001116118; NP_001166138; NP_057574; NM_001122646; NM_001172667; NM_016490; LOC51252; F178B_HUMAN; Q8IXR5;
More at Entrez
chemokine (C-C motif) ligand 24 [Source:HGNC Symbol;Acc:10623]
Functions:
Synonyms: ENSG00000106178; ENSP00000222902; ENSP00000400533; 6369; CCL24; NP_002982; NM_002991; Ckb-6; eotaxin-2; MPIF-2; MPIF2; SCYA24; CCL24_HUMAN; O00175;
More at Entrez
naked cuticle homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:17046]
Functions:
Synonyms: ENSG00000145506; ENSP00000274150; ENSP00000296849; ENSP00000372177; ENSP00000440925; 85409; NKD2; NP_149111; NM_033120; Naked2; NKD2_HUMAN; Q969F2;
More at Entrez
sterile alpha motif domain containing 11 [Source:HGNC Symbol;Acc:28706]
Functions:
Synonyms: ENSG00000187634; ENSP00000342313; ENSP00000349216; ENSP00000393181; ENSP00000411579; ENSP00000412228; 148398; SAMD11; NP_689699; NM_152486; MGC45873; Q96NU1; SAM11_HUMAN;
More at Entrez
PHD finger protein 23 [Source:HGNC Symbol;Acc:28428]
Functions:
Synonyms: ENSG00000040633; ENSP00000043410; ENSP00000322579; ENSP00000414607; 79142; PHF23; NP_077273; NM_024297; FLJ16355; hJUNE-1b; MGC2941; PHF23_HUMAN; Q9BUL5;
More at Entrez
mutY homolog (E. coli) [Source:HGNC Symbol;Acc:7527]
Functions:
Synonyms: ENSG00000132781; ENSP00000346354; ENSP00000347685; ENSP00000361170; ENSP00000361172; ENSP00000361176; ENSP00000361182; ENSP00000361187; ENSP00000403655; ENSP00000407590; ENSP00000408176; ENSP00000409718; ENSP00000410263; ENSP00000431264; ENSP00000431292; ENSP00000431568; ENSP00000432330; ENSP00000432528; ENSP00000433076; ENSP00000433130; ENSP00000433476; ENSP00000433843; ENSP00000434985; ENSP00000435889; ENSP00000436430; ENSP00000436469; ENSP00000436478; ENSP00000436597; ENSP00000437093; ENSP00000437166; 4595; MUTYH; NP_001041636; NP_001041637; NP_001041638; NP_001041639; NP_001121897; NP_036354; NM_001048171; NM_001048172; NM_001048173; NM_001048174; NM_001128425; NM_012222; MYH; MUTYH_HUMAN; Q9UIF7;
More at Entrez
SH3 and cysteine rich domain 3 [Source:HGNC Symbol;Acc:28423]
Functions:
Synonyms: ENSG00000185482; ENSP00000329200; ENSP00000441515; ENSP00000450740; ENSP00000452068; ENSP00000452299; 246329; STAC3; NP_659501; NM_145064; MGC2793; Q96MF2; STAC3_HUMAN;
More at Entrez
glycogen synthase kinase 3 alpha [Source:HGNC Symbol;Acc:4616]
Functions:
Synonyms: ENSG00000105723; ENSP00000222330; ENSP00000381301; ENSP00000412663; ENSP00000442593; 2931; GSK3A; NP_063937; NM_019884; GSK3A_HUMAN; P49840;
More at Entrez
zinc finger protein 354B [Source:HGNC Symbol;Acc:17197]
Functions:
Synonyms: ENSG00000178338; ENSP00000327143; ENSP00000429827; 117608; ZNF354B; NP_478137; NM_058230; FLJ25008; KID2; Q96LW1; Z354B_HUMAN;
More at Entrez
orthodenticle homeobox 1 [Source:HGNC Symbol;Acc:8521]
Functions:
Synonyms: ENSG00000115507; ENSP00000282549; ENSP00000355631; ENSP00000385782; 5013; OTX1; NP_001186699; NP_055377; NM_001199770; NM_014562; OTX1_HUMAN; P32242;
More at Entrez
tRNA splicing endonuclease 54 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:27561]
Functions:
Synonyms: ENSG00000182173; ENSP00000327487; ENSP00000406559; ENSP00000438169; 283989; TSEN54; NP_997229; NM_207346; PCH2A; PCH4; sen54; SEN54L; Q7Z6J9; SEN54_HUMAN;
More at Entrez
CCAAT/enhancer binding protein (C/EBP), epsilon [Source:HGNC Symbol;Acc:1836]
Functions:
Synonyms: ENSG00000092067; ENSP00000206513; 1053; CEBPE; NP_001796; NM_001805; C/EBP-epsilon; CEBPE_HUMAN; Q15744;
More at Entrez
RNA binding motif protein, X-linked-like 1 [Source:HGNC Symbol;Acc:25073]
Functions:
Synonyms: ENSG00000213516; ENSP00000318415; ENSP00000446099; 494115; RBMXL1; NP_001156008; NP_062556; NM_001162536; NM_019610; Q96E39; RBMXL_HUMAN;
More at Entrez
solute carrier family 16, member 11 (monocarboxylic acid transporter 11) [Source:HGNC Symbol;Acc:23093]
Functions:
Synonyms: ENSG00000174326; ENSP00000310490; ENSP00000394449; 162515; SLC16A11; NP_699188; NM_153357; FLJ90193; MCT11; MOT11_HUMAN; Q8NCK7;
More at Entrez
| query genes | n/a | 1 / 1 |
| cardiac muscle cell development | 8.58E-1 | 2 / 16 |
| cardiac cell development | 8.58E-1 | 2 / 16 |
| viral assembly, maturation, egress, and release | 8.58E-1 | 2 / 14 |
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B8FBDC72EEA52C07BEDAC0B0D3864634.genemania